A practical manual for veterinary clinicians on topical and regional iodine use, outlining clinical indications, the principal preparations (tinctures, ointments, aqueous and oily solutions), and their differing local and occasional systemic effects. It stresses the importance of choosing the appropriate formulation for specific pathological conditions, describes methods of application, and highlights observable physical and clinical phenomena that guide treatment. The text examines iodine's limited compatibility with other agents, advises on safe and ethical practice grounded in clinical observation, and offers a framework for classifying cases to obtain more consistent therapeutic outcomes.