A philosopher argues for a foundational account of knowledge and reality by asserting an Absolute that transcends human conception and by treating the Unknowable as the point of reconciliation between scientific inquiry and religious feeling. He derives broad laws said to apply across all classes of phenomena and outlines how these first principles will inform systematic studies of organic life, mental processes, social institutions, and moral conduct. The work emphasizes inductive generalization, frames evolution and developmental change as explanatory tools, and presents a programme for applying these core concepts throughout a comprehensive synthetic philosophy.