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Observations on the Operation and Use of Mercury in the Venereal Disease cover

Observations on the Operation and Use of Mercury in the Venereal Disease

Chapter 6: CHAP. IV.
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About This Book

A medical treatise investigates the application of mercury to venereal disease, opening with the metal's general properties and a critical review of prevailing theories about how it cures, including ideas that it acts by producing evacuations or by neutralizing venereal matter. It surveys mercurial preparations and differentiates topical compounds from systemic formulations, discusses administration techniques and practical cautions, and argues that understanding mechanism improves safe, effective use. The author combines clinical observation with theoretical analysis and calls for continued inquiry to refine dosing, selection of preparations, and measures to minimize toxic effects.

CHAP. IV.

Of the different Mercurial Preparations employed in Medicine.

Metallic substances in general, when employed for the purposes of medicine, have been used in many different forms: But none of them, perhaps, has been exhibited in a greater diversity of preparations than mercury. Some mercurial preparations have never been employed in the cure of lues venerea; and many formerly in use are entirely banished from the present practice in this disease. All these may be considered as unconnected with the subject here treated of. But that the nature of those preparations which are at present most frequently employed, may be more clearly understood, there will be no impropriety in taking a general view of all the preparations of mercury.

The mercurial preparations admitted by the Colleges of London and Edinburgh, contain the most useful and most elegant forms employed in practice, at the time when the last editions of their Pharmacopœias were published. But even at that time they were by no means to be considered as compleat lists. And, since that time, other preparations of utility in practice have been discovered.

A more full view of mercurial preparations than can be obtained from these lists, and, at the same time, some information with regard to the circumstances in which they differ from each other, may be had from a table of mercurials lately published by Dr Saunders of London. In that table, which, with a very few inconsiderable alterations, is the same with one formerly given out by Dr Cullen, when professor of chemistry at Edinburgh, the different mercurial preparations are reduced to general heads, according to the means employed to render them active. From it, the following is almost entirely copied. The names of the different preparations are here printed in Italics, and taken from the London and Edinburgh Dispensatories, from the new Dispensatory, and from the Edinburgh Pharmacopœia Pauperum. To these are added, some mercurials introduced by Boerhaave, Astruc, Keyser, and Plenck. From the letters subjoined to each, it will appear from whence the preparations are taken; and, where an asterisk is prefixed to any one, it denotes, that it is to be considered as perfectly analogous to that immediately preceeding.