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The Glands Regulating Personality / A Study of the Glands of Internal Secretion in Relation to the Types of Human Nature

Chapter 19: INDEX
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About This Book

The work traces the discovery and anatomy of internal secretion glands and explains how their chemical secretions form an interlocking endocrine network involving thyroid, pituitary, adrenals, gonads, and thymus. It describes how hormonal activity influences growth, metabolism, sexual differentiation, and physiological rhythms, and examines mechanisms by which glands shape body and behavior. The text then considers how endocrine variations correspond to temperaments and types of personality, presents historic exemplars for illustration, and discusses clinical applications and possible implications for human evolution, integrating physiological detail with psychological and social perspectives.

As architects of human qualities the endocrines must be involved in the Mendelian unit factors. Moreover, they seem to act upon a particular locale in different degrees, which is the strongest argument against the resolution of a number of structural traits into Mendelian unit characters. Most characters, somatic or psychic, are the products not of the action of one internal secretion alone, but of the interlinked activities of all of them. The amount of fat deposited under the skin, for instance, is influenced by the pituitary, the thyroid, the pancreas, the liver, the adrenals and the sex glands. Other qualities, likewise, are resultants of a compromise between all the endocrine factors comprising the equation of the individual. If we are to look for unit factors at all in endocrine heredity, we must look more deeply into constitution, and measure the hormone potentials and their mobilization or suppression.

It will, in all probability, be found that the stability or instability of an endocrine will have a good deal to do with the part played by it in inheritance as well as in the life of the individual An unstable pituitocentric marrying another unstable pituitocentric will have children either exceptionally small or tall, or abnormally bright or stupid. The instability tends to right itself in the next generation, or that following. Genius as a sport, as well as sudden degeneration of family stock, the whole problem of mutation, may be closely connected with this tendency.

It has been noted that the extinction of species has been preceded by a great increase in their size, for example, the case of the great reptilia of prehistoric time. That possibly represented pituitary stabilization, and so an abeyance of the ability to vary, necessary for fresh adaptation to a changing environment. Indeed, endocrine instability appears the fundamental condition of the tendency to vary, endocrine stability the opposite.

Certain endocrine facts in relation to heredity should be mentioned. The daughters of mothers who menstruated early, themselves menstruate early. Animals fed upon thyroid during pregnancy, comparable to the thyrocentric, give birth to offspring with a very large thymus, comparable to the thymocentric. Women with partial thyroid deficiency, or myxedema, bear cretins. These are suggestive of what the internal secretions may do to an individual in inheritance and development. Inherited endocrine potential is the maximum reaction of which a gland is capable. This matter of potential is comparable to the factor of reserve power or margin of safety demonstrated up to the hilt for such organs as the heart and kidney as varying from individual to individual. A low potential, like instability of an internal secretion gland, may be latent, and not made manifest until the proper stimulus, the maximum amount of stress and strain, like accident, disease, shock or war, arrives.

When the individual is tested the effects may be purely local because there is always in the organism a point of least resistance. Physical changes alone may be prominent. Or because somatic changes are minor, the psychic will dominate the picture. An attack of the "blues," unaccompanied by any demonstrable transformation of the bodily processes, may be the sole symptom of an endocrine failure somewhere in the chain due to hereditary weakness or low potential.

So we may account for family trends and streaks, for varieties and strains among individuals, upon more precise lines based upon endocrine analysis. Family disturbances of the internal secretions of the extreme sort denominated disease are well known. Indeed, a number of family diseases or predispositions to diseases, have been traced to them. Predisposition in any direction will probably be shown to be caused by them, within limits. Research here has its opportunity.

THE IMPROVEMENT OF RACIAL STOCK

A vast new territory of inquiry and achievement, as yet totally unexplored, is opened by the endocrines to the eugenists, and those idealists whose most earnest aspiration is the improvement of racial stock as a necessary preliminary to improvement of racial life. Beginning with Galton, they have brought to light a great collection of data to prove that human traits and faculties, good and bad, are inherited. Ability has been shown to run in certain families and degeneracy in others. Yet all of the practical net result has been summed up in the term "negative eugenics," the eugenics of prohibition and warning.

Now the concept of personality, as woven around a system of chemical reflexes, handed on from generation to generation, is bound to change all that, and to create a structure of positive eugenics. It has been said that what radium is to chemistry, the internal secretions are to physiology. Just as radium enlightens the chemist about the history of matter, and the integrations and disintegrations constituting the life of an element—the internal secretions illuminate the history of the individual as part of the life of the race, and of its integrations and disintegrations. Seeing the individual as a system of chemical substances interacting will assist enormously to predict the nature, character and constitution of his descendants, which is essentially what the eugenist is after.

The study of matings, the heart of the matter, will concern itself with the investigation and comparison of the kind of endocrine personalities that mate, the internal secretion predominances that cross, and the consequent endocrine personality of the offspring. Data bearing upon physique and physiognomy, details of anatomy and function, mind and behaviour will so be co-ordinated as no eugenist has hitherto succeeded in doing. Laws of endocrine inheritance will emerge that will bring the control of heredity within measurable distance. Standards and norms of a new kind would be obtained.

A beginning of this study of endocrine inheritance, on the pathologic side, has been made. Some of these have been along Mendelian lines. Following up abnormal growth (making giants and dwarfs) and abnormal metabolism (goitre, diabetes, and so on), it has been stated that it would seem that abnormal growth is dominant in the male, and recessive in the female, while abnormal metabolism is dominant in the female and recessive in the male. If an endocrine abnormality like a goitre, or cretinism, or a dwarf or giant appear in a family as a sign of endocrine instability, other members of that family will very likely show internal secretion abnormalities.

If one gland of internal secretion acts as the centre of the system and the others as satellites, we should be able to trace what happens to it in the different generations. Does it maintain its supremacy? Or will it be ousted by another member of the group? The time will come when we shall thus be able to advise prospective parents of the consequences of procreation and to forecast the meaning for the race of a particular marriage. Internal glandular analysis may become legally compulsory for those about to mate before the end of the present century.

What are desirable and undesirable matings? The general law followed by nature in her helterskelter way seems to be the production of the greatest number of hybrids and variations possible, whether for good or evil does not matter. Certain endocrine types appear to be specially attracted to others belonging to the same group. Thus thymus-centered types frequently marry. The ante-pituitary type of male, the strongly masculine, mates often with the post-pituitary type of female, the markedly feminine. The children exhibit the lineaments of the pituitary-centered type. The general trend seems to be the establishment of a better balanced, equilibrated type. Yet the children often are apt to segregate into pituitary dominants or pituitary deficients. Happiness and unhappiness in marriage should be examined from the standpoint of endocrine compatibility or incompatibility. Likewise those divorced or about to be divorced.

The correction of endocrine defects, disturbances, imbalances and instabilities, before mating, presents another field. It remains to be seen whether we shall thereby, in one generation, be able to affect at all the germplasm, hitherto revered by all pious biologists as an environment-proof holy of holies. No one can deny, in the face of the multitude of evidence available, that internal secretion disturbances occur in the mother, which, when grave, offer in the infant gross proof of their significance, and therefore when slight must more subtly work upon it. Endocrine disturbances in infancy have been traced to endocrine disturbances in the mother during pregnancy. Pregnant animals fed on thyroid give birth to young with large thymus glands. The diet of the mother has been proved conclusively to influence the development and constitution of the child. As the internal secretions influence the history of the food in the body, they affect development in the womb indirectly as well as directly. Certainly, whether or no we learn how to change the nature of germplasm within a short time, we have in the endocrines the means at hand for affecting the whole individual that is born and sees the light of day.

THE CONTROL OF MUTATIONS

The true physical and intellectual evolution of man depends upon the production of mutations of a desirable kind that can survive. The information furnished by the study of the endocrines concerning the genesis of personality provides the foundations for a positive eugenics, a eugenics of the encouragement of desirable matings, with the proper legal and social procedures. Selective breeding for the production of the best endocrine types should become practicable.

But the biologist should be able to go farther. If the eugenist is to limit himself to the method of the animal breeder he will have to rest satisfied with the characters or hereditary factors given, that turn up spontaneously in an individual. But with the internal secretions as the controllable controllers of mutations, the outlook changes. It should become possible to produce new mutations, good and bad, to speed up their production at any rate. The feeding of thyroid to a gifted father before procreation might enhance immeasurably the chances of transmission of his gift as well as of its intensification in his offspring. A field of investigation is opened that would embrace in due time the deliberate control of human evolution.

All the physical traits, stature, color, muscle function, and so on, offer themselves for improvement, as well as brain size, and the intellectual and emotional factors which have dominated man's social evolution. The general prevalence of nervous disorders in civilized countries, visible even in the nervous infants the specialist in children's diseases is called upon to treat, shows that the nervous system of the better part of mankind is in a state of unstable equilibrium. It may be another example of the curious coincidences that have been called the Fitness of the Environment that the investigation of the endocrines promises to put into our hands the instruments of the control of the future of the nervous system. In general, meanwhile, the eugenist should strive for raising the level of the endocrine potential, and discourage its lowering. That means the encouragement of matings in which all the internal secretion activities are reinforced. On the other hand, those internal secretion combinations, generally leading to a deficiency of all of them which produce types of mental defectives, delinquency and crime should not be allowed to occur.

THE INFLUENCE OF ENVIRONMENT

What suggestions now are there for the euthenist who would control the influence of environment upon child culture. There are certain pertinent facts and leads that are worth considering.

In analyzing environment, one must distinguish sharply in the jungle, the non-living factors from the living. For while the nonliving act upon the endocrines directly, the living act upon the vegetative system, as a whole. The non-living factors are those with the intimate scrutiny of which physics and chemistry have busied themselves: food, water, air, light, heat, electricity, magnetism. The living are the animals that prowl all over the planet, the predatories spreading the gospel of fear.

The dietetic habits of a person, for instance, are known to have an influence upon the glands of internal secretion. Meat-eating produces a greater call upon the thyroid than any other form of food. In time this ought to produce a degree of hyperthyroidism in the carniverous populations. Pre-war statistics concerning meat-eating in different countries show the greatest meat-eating among the English-speaking groups, who all in all must be admitted the most energetic.

Meat per Day per Countries Capita in Grams

  Australia 306
  U.S. of America 149
  Great Britain 130
  France 92
  Belgium and Holland 86
  Austria-Hungary 79
  Russia 59
  Spain 61
  Italy 29
  Japan 25

Sea-water contains iodine. People living in contact with sea-water would be apt to get more iodine in their systems, and so a greater degree of thyroid activity. On the other hand, certain bodies and sources of inland water hold something deleterious to the thyroid, so that whole populations in Europe, Asia and America drinking such water have become goitrous and cretinous, and a large percentage straight imbeciles. Endemic cretinism is the name given to the condition. In parts of Switzerland, Savoy, Tyrol and the Pyrenees, in America around some of the Great Lakes, there are still such foci. Marco Polo described similar areas he encountered in his travels through Asia.

Certain foods with aphrodisiac qualities may act by stimulating the internal secretion of the sex glands. A type of pituitocentric has an almost uncontrollable craving for sweets. Alcohol and the endocrines remain to be studied.

Light, heat and humidity stand in some special relation to the adrenals. Pigment deposit in the skin as protection against light is controlled by the adrenal cortex. The reaction of the skin blood vessels to heat and humidity is regulated by the adrenal medulla. A change in the adrenal as a response to changes of temperature and humidity in an environment would result in a number of concomitant transformations throughout the body. So variation and adaptation are probably connected. Most Europeans living for a sufficiently long time in the tropics suffer from a combination of symptoms spoken of as "Punjab head" or "Bengal head." The condition is probably the result of excessive adrenal stimulation by the excessive heat and light of the tropical sun, followed by a reaction of exhaustion and failure, with the consequent phenomena of a form of neurasthenia. In the section on the pineal gland there was mentioned the relation between light and the pineal gland in growing animals, and how it serves to keep in check the sex-stimulating action of light. The earlier puberty and menstruation of the warmer climates may be explained as due to an earlier regression of the pineal under the pressure of a great amount of light playing upon the skin.

All these, and many more could be cited, are instances of the direct influence of environmental factors upon one or more of the endocrines, and so upon the organism as a whole. Indeed, stimuli may be considered to modify an organism only in so far as they modify the glands of internal secretion. Consequently, climatic factors will tend to make a population possess certain points of resemblance in common.

Varieties of the human race exist as do varieties of dogs. The pekingese and the fox terrier are as different as the Slav and Latin are different: because of differences in internal secretion make-up. The Slav peasant is definitely subthyroid in his general effect: round head, coarse features, stubby hands, and his stolid, brooding intellectual and emotional reaction. The Latin shows a pronounced adrenal streak in his coloration, his emotivity, his susceptibility to neurosis and psychosis. H. Laing Gordon, a Scot physician, reported that of 700 cases he studied, more than twice as many of duplex eyed individuals (brown or black, i.e., adrenal-centered most often), were susceptible to the mental disturbances of war as the simplex (blue or gray-eyed, i.e., thyroid-centered most often). He also pointed out that such individuals tend to have a narrow and abnormally arched palate. The Anglo-Saxon tends to be more sharply pituitarized, his features are more clean-cut, his mentality more stable. The Frenchman is rather a cross between the Anglo-Saxon pituitary-centered and the Italian or Spanish adrenal-centered.

So national resemblances, traceable to climatic influences being repeated from generation to generation upon the endocrines, may be explained physiologically. The physiologic interpretation of history will indeed be found the broadest, including as complementary Buckle's climatic theory, Hegel's ideas on the influence of ideas, and Marx's on the superiority of the economic motives and forces.

THE RACES OF MANKIND

Arthur Keith, conservator of the Museum of the Royal College of Surgeons of England, was the first to apply the principle of endocrine differentiation to the problem of the color-lines—the lines which have divided mankind crudely into the yellow, the red, the white and the brown, the Negro, the Mongol, the Caucasian, the copper tinted American. It has long been recognized by anthropologists that the differences of color march with differences in every comparable trait. Thus the ideal Negro is built upon a pattern in which all the elements are specific and singular. When the looms revolve that make him, there is produced a gleaming black skin, kinky black hair, squat wide-nostriled nose, thick protruding lips, large striking teeth, prominent jaws, and staring eyes. As his upright carriage and bone-muscle-fat proportions are distinctive, so are his musical voice and his easily wrought upon nerves. In contrast the Caucasian has a good deal of hair on his body, his skin is a pale tan-pink, his lips are thin, and his nose especially has the definite bridge which narrows it. The Mongol, like the Negro, has the hairless body and the beardless face, but unlike him has lank straight hair on his head, while his features are flattened and fore-shortened.

Upon the basis of these structural, functional and mental differences, the qualitative and quantitative evolution of which in the race as in the individual is guided by the glands of internal secretion, Keith presents a very good case for the view that the white man is an example of relative excess of the pituitary, thyroid, adrenal and gonad endocrines. "The sharp and pronounced nasalization of the face, the tendency to strong eyebrow ridges, the prominent chin, the tendency to bulk of body, and height of stature in the majority of Europeans" are the signs of pituitary dominance. Keith is also of the opinion that "the sexual differentiation, the robust manifestations of the male characters, is more emphatic in the Caucasian than in either the Mongol or Negro racial types … in certain negro types, especially in Nilotic tribes, with their long stork-like legs, we seem to have a manifestation of abeyance in the action of the interstitial glands." As for the adrenal superiority of the white man, "it is 150 years since John Hunter came to the conclusion … that the original color of man's skin was black, and all the knowledge that we have gathered since his supports the inference he drew. From the fact that pigment begins to collect and thus darken the skin when the adrenal bodies become the seat of a destructive disease we infer that they have to do with the clearing away of pigment, and that we Europeans owe the fairness of our skins to some particular virtue resident in the adrenal bodies." Finally, as regards the thyroid, a comparison of the face of a cretin with that of the Negro or Mongol tells the story. A certain variety of idiocy, Mongolian idiocy, in which the face simulates cretinism so closely as to deceive practised clinical observers, is characterized by a Chinese cast of the features and eyes, hence the name. And in the Bushman of South Africa, the cretin's face is even more startlingly recalled.

There is every reason then for believing that the white man possesses more of pituitary, adrenal, gonad, and thyroid internal secretions as compared with the yellow man or black man. And since these endocrines control not only physique and physiognomy, anatomic and functional minutiae, but also mind and behaviour, we are justified in putting down the white man's predominance on the planet to a greater all-around concentration in his blood of the omnipotent hormones. While the Negro is relatively subadrenal, the Mongol is relatively subthyroid. Their relative deficiency in internal secretions constitutes the essence of the White Man's Burden.

MAN'S ATTITUDE TOWARD HIMSELF

A last, but by no means least, application we may consider of the developing knowledge of the internal secretions in relation to human evolution is its effect upon Man's attitude toward himself and so toward his fellow men. Whatever else he is, man is a land animal with ideas. That makes him a thought-adventurer among materials. In a word, he is the last word of mind working upon matter. But persistently he has refused to recognize himself as matter and as subject to the laws, to the physics and chemistry of matter.

History consists of the protocols that record the high lights of the interactions of materials and ideas which is the adventure of man in time and space. Materials and ideas have reacted, the record shows; materials come upon have begotten strange fantasies. Ideas that flashed from nowhere into a consciousness have transformed utterly the face of the earth. The herd-brute, agglutinated with his fellows by a magnetism beyond his ken, could be infected with thought, and so cast in the heroic mould. The possibility of communion,—that possibility of possibilities, for without it none other could be possible—has rendered man the heir of a divine destiny. For the progressive education of the race, a single discoverer here, an inventor there, and thinkers everywhere have been inspired. In due time their inspiration becomes the possession of even the lowest brain but capable of grasping it.

Man's attitude toward himself, his self-consciousness, and his attitude toward his fellow creatures has grown and varied and evolved with his education about himself. According to the theory he formulated concerning his being, his why and wherefore, he directed and governed, punished and mutilated himself and them. But the pressure of his curiosity, and the inexorable quality of the truth would not let him stand still. The poetic genius within him, as Blake called it, struggled on from one dogma concerning his nature to another. Behaviour malignant or beneficent, horrible in its tragedy and pitiable in its comedy, flowed inevitably on. Witchcraft trials and the tortures of the Spanish Inquisition belong among the more mentionable consequences of some of man's theories about his own nature and its requirements.

Heretofore the imaginative spirit has had its day in the matter. And, curiously enough, an obsession to subjugate the natural has made it exalt the supernatural. Visions, dreams, portents, revelations, all symptomatic of an order of things above nature, are the stuff of what more than ninety-nine per cent of the millions of the race believe about themselves and their fate. Man's cruelty to man, through the ages, is a comment upon how vast and ramifying may be the consequences of a delusion.

But now for a couple of centuries the critical spirit, which is the spirit of science, has been invading the affairs of men. Humble but persistent corrosive of delusion, it has infiltrated the furthest bounds of ignorance and superstition. It has not dared to assert the supremacy of its fundamental views upon the everyday problems of human life because it was without concrete means of vindicating its claims. That lack is now supplied by the growing understanding of the chemical factors as the controllers and dictators of all the legion aspects of life.

The profoundest achievement of the physiologist will be the change his teachings and discoveries will bring about in man's attitude toward himself. When he comes to realize himself as a chemical machine that can, within limits, be remodeled, overhauled and repaired, as an automobile can be, within limits, when he becomes saturated with the significance of his endocrine-vegetative system at every turn and move of his life, and when sympathy and pity informed by knowledge and understanding will come to regulate his relationships with the lowest and most despised of the men, women and children about him, the era of the first real civilization will properly be said to be born.

Morality, as society's code of conduct for its members, will have to change in the direction of a greater flexibility with the establishment of organic differences in human types. There is nothing that is more emphasized to the pathologist than that one man's meat is another man's poison. In the family, as nature's laboratory for the manufacture of fresh combinations of the internal secretions, allowances will be made for divergences in capacity and deportment from a new angle altogether. Schools will function as the developers, stimulators and inhibitors of the endocrines, as well as investigators of the individuals who have not enough or too much of one or some of them. Prisons will have the same function, only they will be named detention hospitals. The raising of the general level of intelligence by the judicious use of endocrine extracts will mean a good deal to the sincere statesman. The average duration of life will be prolonged for an enormous mass of the population. If the prevention of war depends upon the burning into the imagination of the electorates what the consequences of war are, a high intelligence quotient and revaluation of life will count for a good deal.

Man is the animal that wants Utopia. So long as human nature was looked upon as fixed constant in the ebb and flow of life, a Utopia of fine minds could be conceived only by the dreamer and poet. The desire for such a Utopia could only be regarded as a tragic aspiration for an impossibility. The physiology of the internal secretions teaches that human nature does change and can be changed. A relative control of its properties is already in view. The absolute control will come.

Nor need anyone fear that the science of the internal secretions in its maturity will signify the abolition of the marvelous differences between human beings that create the unique personalities of history. A derangement of the endocrines has been responsible for masterpieces of the human species in the past and will be responsible for them in the future. The equality of Utopia can be the equality of the highest and fullest development possible for each of its inhabitants. The applications of endocrine control will not necessarily interfere with the life of the individual. There will be breeding of the best mixtures of glands of internal secretion possible. And there will be treatment for those born with a handicap, or who have become handicapped in the life struggle. There will be a stimulation of capacity to the limit. But beyond that, compulsory equalization is a theorist's bogey.

The internal secretions are the most hopeful and promising of the reagents for control yet come upon by the human mind. They open up limitless prospects for the improvement of the race. A few hundreds of investigators are engaged upon their study throughout the world. That is one of the ironies of our contemporary civilization. A concerted effort at the task of understanding them, backed by the labors of tens of thousands of workers, would, without a doubt, accomplish as much for humanity as the vast armies and navies that consume the substance of mankind. If we could not obtain Utopia then, we might, at least by abolishing the subnormals and abnormals who constitute the slaves and careerists of society, render the human race less contemptible and more divine.

INDEX

 Ability, natural
  Acquired characters, inheritance of
  Acromegaly
  Addison
  Addison's disease
  Adolescence, period of
  Adrenal glands
    and anger
    and courage
    and emergencies
    and emotions
    and fatigue
    and fear
    and neuroses
    and pseudo-hermaphroditism
    and puberty
    blood pressure and
    brain cells and
    chromaffin cells of
    cortex of
    excess of secretion
    failure of secretion
    function of
    glands of combat and fight
    hair and
    influence of in hermaphroditism
    insufficiency of secretion
    medulla of
    pigment cells and
    relation to pineal gland
    relation to pituitary
    secretion of
    sexuality and
    skin and
  Adrenal-centered type
  Adrenal face
  Adrenal personalities, or types
    compensated
    insufficient
    in pregnancy
    of brain work
    of girl
    of hair
    of skin
    of teeth
  Adrenal personalities, or types of women
    reactions to modernism in
  Adrenalin
  Alcoholism and endocrine types
  Analysis, endocrine
  Anger
    and adrenals
  Antagonisms
  Anti-Fate
  Antitoxic function of thyroid gland
  Ape-parvenu, the
  Applications of endocrinology
  Autonomic system

  Backgrounds of personality
  Baldness and the thyroid
  Baumann
  Bayliss
  Beard
  Beard's neurasthenia
  von Bechterew
  Behavior
  Bell, Blair
  Bernard, Claude
  Berthold
  Black races, endocrine control in
  Blood pressure, and adrenals
  Body, influence of glands upon
  Body-mind complex
  Bones
    long, development of
  Bordeau
  Bossi
  Brain cells and adrenals
  Brain, growth of
  Brainwork, adrenal type of
  Breakdown, nervous
  Breeding, bearing of endocrine glands on
  Brown-Séquard

  Caesar, Julius, an epileptic
    pituitary in
  Capacity
  Careerist
    as abnormals
    feminine
    instincts of
    masculine
    super-
  Carlson
  Castration
    effects of
    effects of, on thymus
  Character
  Charcot
  Charging of wishes, endocrine
  Check and drive system
  Chemistry of the soul
  Child—bearing, transfigurations of
  Childhood, epoch of the pineal
  Chromaffin cells of adrenals
  Chromosomes
  Climacteric
  Color, endocrine control of, in races
  Combat, adrenals and
  Combinations of types of personality
  Conduct
  Constitutions, endocrine
  Cooperation
  Corpus luteum
    and mammary glands
  Courage and the adrenals
  Cretinism
    a thyroid deficiency
    effect of feeding thyroid in
  Cretinoid type
  Cretin
  Crime, treatment of
  Criminals and endocrine types
  Critical ages
  Curling
  Cushing, Harvey

  Dangerous age, the
  Darwin, Charles
    as a neurasthenic genius
    his "Descent of Man"
    his theory of Pangenesis
  Davenport
  Deficiency, mental
  Development
  Diabetes, and the pancreas
  Diet, effect of on the endocrine glands
  Directorate, endocrine glands as a
  Diseases and endocrine types
  Division of labor
  Drug addiction and endocrine types
  Dwarfs

  Education, of vegetative-system
    vocational
  Egomania
  Elixir of life
  Emergencies, adrenals glands of
  Emotions, adrenals glands of
  Endocrine
    analysis
    charging of wishes
    constitutions
    control in color of races
    corporation
    deficiency in old age
    epochs of life
    glands
      and feeblemindedness
      and insanity
      as an interlocking directorate
      bases of variation
      bearing on breeding
      discovery of
      effect of diet on
      influence upon body
      influence upon mind
    inferiority
    neurosis
    personality
    sex traits
    types
      alcoholism and
      criminals and
      diseases and
      drug addiction and
      narcotism and
  Endocrines, evolution of
  Endocrinology, applications of
    possibilities of
  Energy
    and thyroid
  Enthusiasm and thyroid
  Environment, influence of
  Epilepsy, in genius
  Epochs of life, endocrine
  Eugenics, negative
    positive
    promises of
  Eunuchoid face
    personality
  Eunuchoidism
  Eunuchs
  Evolution, human, effect of internal secretions upon
  Exhibitionism
  Expressionism
  Eyes

  Face, adrenal
    eunuchoid
    hyperpituitary
    hyperthyroid
  Facial types
  Family, and mixed sex
  Fat, distribution of
  Fat people
  Fate and Anti-Fate
  Fatigue and industry
    as an endocrine deficiency
    relation of adrenals to
    relation of thymus to
  Fear
    mechanism of
    relation of adrenals to
  Feeblemindedness and the endocrine glands
  Feminine pituitary type
  Feminine precocity
  Feminoid complex
    constitution and personality
  Fertilization
  Fight, relation of adrenals to
  Fingers, pituitary and
    thyroid and
  Forgetting
  Freedom
  Freud
  Freudianism
  Freudians
  Friedleben

  Galli
  Galton
  Genius, epilepsy in
    migraine in
    neurasthenic
    treatment of
  Giants
  Girl, endocrine types of
  Glands, definition of
    endocrine, as an interlocking directorate
    discovery of
    influence on body
    influence on mind
  Goitre, relation of iodine to
  Gonads
    and libido
    and sexuality
    and thymus
  Gonads and thyroid
    function
    secretion
  Gonad-centric personalities
    homosexuality and
  Growth
    relation of thymus to
  Guilford
  Gull

  Hair
    and adrenals
    and pineal
    and thymus
    and thyroid
  Hands, and pituitary
    and thyroid
  Henle
  Hermaphrodite
  Hermaphroditism
    functional
    influence of adrenals in
    influence of pituitary in
  Hibernation
    and the pituitary
  Historic personages
    Darwin, Charles
    Julius Caesar
    Napoleon
    Nietzsche
    Nightingale, Florence
    Wilde, Oscar
  History, internal secretions in
  von Hochwart
  Homosexuality, and gonad-centric type
    and thymus type
  Hormones
    harmony of the
  Horsley
  Howitz
  Human nature
    attitudes towards
    case against
    science and
  Hunger
  Hunter, John
  Hygiene of the internal secretions
  Hyperpituitary face
    skin
  Hyperpituitrism,
  Hyperthyroid face
    skin
    type
      of girl
      pregnancy in
      premenstrual molimina in
  Hyperthyroidism
  Hysteria

  Imagination, an endocrine gift
  Improvement of racial stock
  Industry, and fatigue
    relation of endocrines to
  Infancy, epoch of the thymus
  Infantilism
  Infantiloid constitution or personality
  Inferiority, breeding of
  Inheritance of acquired characters
  Insanity, and the endocrine glands
  Instinct
  Instincts, pituitary
    thyroid
  Insuline
  Intellectuality, and the pituitary
  Internal secretions, determinants of vegetative pressures
    effect of, upon human evolution
    hygiene of
    in history
  Interstitial glands, see Gonads
    type of teeth
  Iodine, in thyroxin
    relation of to goitre

  Janet
  Judgment
  Julius Caesar, an epileptic
    pituitary in

  Keith
  Kendall
  Kinetic chain
    drive
    system
  Kocher

  Laennec
  Lanugo
  Larey
  Libido and gonads
    sex
  Life, well-springs of
  Lime salts, and sex
  Lincoln, Abraham
  Lutein

  MacDougallians
  Malthusian law of slavery
  Mammary glands
    corpus luteum and
    placenta and
  Man, a transient
    attitude of towards himself
    a product of glands of internal secretion
    critical age in
    secondary sex characteristics of
  Manic depressive psychoses
  Mankind, races of
  Marie, Pierre
  Masculine, the secret of the
  Masculine and feminine, mechanics of, and see Sex
  Masculine pituitary type
  Masculinoid women
  Masochism
  Maternal instinct
    different from sex instinct
    relation of the pituitary to
  Matings, desirable and undesirable
  Megalomania
  Memory
  Mendelism
  Menopause
  Menstruation
    and ovaries
    cycle of
  Mental deficiency
  Migraine in genius
  Mind, influence of glands on
    oldest part of
  Mitchell, Weir
  Mixed sex and the family
  Mixed types
  Möbius
  Modernism, reactions to in adrenal types
  Moods, and the organic outlook
  Moral irresponsibility and thymus type
  Mujerados
  Müller, Johann,
  Murray
  Muscles
  Mutations, control of
  Myxedema
    operative

  Napoleon, case of
  Narcotism, and endocrine types
  Nature's experiments vs. Man's
  "Nerves"
  Nervous breakdowns
  Neurasthenia
  Neurosis
    adrenals and
    endocrine
    war
  Nietzsche, case of
  Nightingale, Florence, legend of
  Normal, what is

  Obesity
  Operative myxedema
  Ord, William
  Ovaries, internal secretion of
    relation of to menstruation
    removal of, effect of
    rôle of
  Oversecretion

Pancreas diabetes and function of removal of secretion of Pangenesis, Darwin's theory of Parathyroids function of secretion of Paulesco Pawlov Permutations, of types of personality, Perry, Caleb Personality, background of combinations of types of determined by the endocrines endocrine eunuchoid types of adrenal combinations of gonad-centric nature's experiments vs. man's permutations of pituitary of Philosophers, prejudices of Physics of the wish Physiologists, attitude of rôle of Pigment cells and the adrenals in skin of various races Pineal gland and hair and childhood feeding of to children function of muscle function of Pineal gland, obesity and puberty and relation of to adrenals to progressive muscular atrophy secretion of type of muscles Pituitary gland action of and fingers and toes compared with thyroid diminished action of extirpation of function of in Julius Caesar in Oscar Wilde instincts overaction of personalities regulator of organic rhythms relation to adrenals to growth to hair to hermaphroditism to hibernation to imagination to intellectuality to judgment to maternal instincts to memory to puberty to rejuvenation to sex difficulties to sexual glands to stature to thymus secretion of secretion, characteristics of inferior characteristics of sufficient type feminine masculine of eyes of hands of muscles pregnancy in premenstrual molimina in Pituitary-centered type Pituitocentrics, Caesar Darwin Napoleon Nietzsche Nightingale Pituitrin function of Placenta and mammary glands Placental gland Plater, Felix Plummer Poise Popielski Possibilities of endocrinology Postpituitary type of girl Precocity, feminine male Pregnancy, in various endocrine types Premenstrual molimina, in various endocrine types Progressive muscular dystrophy and the pineal gland Prostate Pseudo-hermaphroditism and the adrenals Psychanalyst, as a therapeutist Psychology, new Psychopathology of every day life Puberty glands, see Gonads in female significance of Public health, prospects of Pure types Puericulture, science of

  Races of mankind
  Reactions to modernism in adrenal types
  Rejuvenation, possibilities of
  Religion of science
  Repression
  Resilience of skin
  Restelli
  Reverdin, J.L.
  Rhythms of sex
  Robertson

  Sadism
  Schiff, Moritz
  Science, and human nature
    origin of
    religion of
  Secondary sex traits
  Secretin
  Secretion
  Sella turcica
  Semon, Sir Felix
  Senility, epoch of endocrine deficiency
    interpretation of
  Sensitivity
  Sex
    and lime salts
    attitudes towards questions of
    cause of
    chemistry of
    characteristics, secondary
    conflict
    crises
    difficulties, pituitary and
    glands, see Gonads
      and hair
      and puberty
      and muscles
      centered
      chain
    index
    instinct
      different from maternal instinct
    libido
    life, determining factors of
    mixed, and the family
    rhythms of
    traits, or characteristics
      endocrine
      origin of
      primary
    secondary
  Sexual cravings
    glands, see Gonads, and Sex glands
      and pituitary gland
  Sexuality, and gonads
    and adrenal glands
  Shaw, G.B.
  Shell-shock
  Skeletal types
  Skin
    adrenal type
    and adrenals
    hyperpituitary type
    hyperthyroid type
    pigmentation
    subadrenal type
    subpituitary type
    subthyroid type
  Slavery, Malthusian law of
    origin of
  Soul, chemistry of the
  Starling
  Statesman, problems of
    why he fails
  Stature, pituitary and
  Status lymphaticus, and thymus type
  Steinach
  Stirner, Max
  Subadrenal skin
  Subpituitary skin
  Subpituitary type of women
    premenstrual molimina in
  Subpituitism
  Subthyroid face
    skin
    type
      of eyes
      of women, pregnancy in
  Subthyroidism
  Sugar metabolism
  Super-Careerist
  Susceptibility
  Sympathetic system

Teeth Tethelin action of function of Thymic face Thymo-centric personalities Thymo-centric type Oscar Wilde Thymus and gonads and pituitary and puberty and sexual glands and thyroid effect of castration on effect of feeding thymus to animals extirpation of function of hair and hyperactivity of infancy, epoch of the persistent, skin of relation of fatigue to relation of growth to relation of weight to removal of, effect on gonads secretion type of teeth Thymus type homosexuality and moral irresponsibility and status lymphaticus and Thyroid gland and adrenals and baldness and energy and enthusiasm and intersitial glands and judgment and memory and pancreas and pituitary Thyroid gland and puberty and rejuvenation and skin and thymus antitoxic function of as an accelerator as a catalyser as a differentiator as an energiser compared with pituitary creator of land animals deficiency effect of feeding the gland excess functions of hair and instincts personalities secretion of, and see Thyroxin type, of eyes of hands of muscles of teeth Thyroid-centered type Thyrotoxin Thyroxin and energy mobilization and energy production and speed of living Toes pituitary and thyroid and Tonus Types endocrine adrenal adrenal-centered alcoholism and combinations of cretinoid criminals and diseases and drug addiction and facial hyperthyroid mixed narcotism and of girls pituitary, pituitary-centered pure skeletal, subthyroid thyroid-centered Unconscious, the and the viscera physical basis of Undersecretion Variation endocrine glands as basis of Varieties of internal secretions Vegetative apparatus Vegetative pressures internal secretions determinants of Vegetative system education of Virilism Viscera the unconscious and Vocational education

  War neurosis
  Weight relation of thymus to
  White races
    endocrine control in
  Wilde, Oscar
    explanation of
  Wishes
    endocrine charging of
    physics of
  Women
    adrenal type of
    masculinoid
    secondary sex characteristics in

X-chromosome

Yellow races endocrine control in