A vividly illustrated narrative retells the early encounters between a young indigenous Virginian girl and an English adventurer as colonists establish a settlement along the river. It follows their separate origins, the arrival of the newcomers, escalating tensions and skirmishes, the explorer's capture and dramatic rescue by the girl, and her efforts to aid the struggling settlers. Later episodes cover her capture by other colonists, a marriage to an Englishman and a visit to the royal court in England, a reunion with the explorer, and her nostalgic longing for home, concluding with a sober reflection on the personal costs of cultural collision.