Alexander VI. (Rodrigo Borgia), August 1492 to 1503.

Pius III. (Francis Piccolomini), September to October 1503.

Julius II. (Julian della Rovere), November 1503 to February 1513.

Leo X. (Giovanni dei Medici), March 1513 to December 1521.

Adrian VI. (Tutor of Charles V.), January 1522 to September 1523.

Clement VII. (Giulio dei Medici), November 1523 to September 1534.

Paul III. (Alexander Farnese), October 1534 to November 1549.

Julius III. (Giovanni Maria del Monte), February 1550 to March 1555.

Marcellus II. (Marcello Cervini), April 1555.

Paul IV. (John Peter Caraffa), May 1555 to April 1559.

Pius IV. (Giovanni Angelo dei Medici), December 1559 to December 1565.

Pius V. (Michael Ghislieri), January 1566 to May 1572.

Gregory XIII. (Hugh Buoncompagno), May 1572 to April 1585.

Sixtus V. (Felix Peretti), April 1585 to August 1590.

Urban VII. (Giovanni Baptist Castogna), September 1590.

Gregory XIV. (Nicholas Sfondrati), December 1590 to October 1591.

Innocent IX. (Giovanni Antony Facchinetti), October to December 1591.

Clement VIII. (Ippolito Aldobrandini), January 1592 to March 1605.