| Page | |||||
|---|---|---|---|---|---|
| Introduction | 9 | ||||
| I. | The Pathology of the Respiratory Tract in Influenza | 13 | |||
| (A) Lesions of the Trachea and Bronchi | 13 | ||||
| (a) Gross Picture | 13 | ||||
| (b) Histological Picture | 14 | ||||
| (c) Summary | 16 | ||||
| (B) Lesions of the Lung | 16 | ||||
| (1) Acute Diffuse Fulminating Type | 18 | ||||
| (a) Gross Picture | 18 | ||||
| (b) Summary | 19 | ||||
| (c) Histological Picture | 20 | ||||
| (d) Summary | 22 | ||||
| (2) Localization and Necrotization of the Pneumonic Process | 22 | ||||
| (a) Gross Picture | 22 | ||||
| (b) Histological Picture | 24 | ||||
| (c) Summary | 26 | ||||
| (3) Organization of the Bronchiolar and Pneumonic Processes | 26 | ||||
| (a) Illustrative Protocols | 27 | ||||
| (b) Summary | 30 | ||||
| II. | Influence of the Respiratory Complications of Influenza upon Tuberculosis of the Lung | 32 | |||
| (a) Illustrative Protocols | 32 | ||||
| (b) Summary | 33 | ||||
| III. | Extrarespiratory Lesions in Influenza | 34 | |||
| (A) Lesions of the Hematopoietic System | 34 | ||||
| (a) Lymphadenoid Tissue | 34 | ||||
| (b) Spleen | 35 | ||||
| (c) Bone Marrow | 35 | ||||
| (B) Lesions of the Blood Vessels and Elsewhere in the Body | 36 | ||||
| (a) Vascular System | 36 | ||||
| (b) Skeletal System | 36 | ||||
| (c) Parenchymatous Organs | 36 | ||||
| (d) Alimentary Canal | 37 | ||||
| (e) Urinary Bladder | 37 | ||||
| (C) Miscellaneous Lesions | 38 | ||||
| (a) Parenchymatous Organs | 38 | ||||
| (b) Jaundice | 39 | ||||
| (c) Central Nervous System | 39 | ||||
| (d) The Pregnant Uterus | 39 | ||||
| (e) Summary | 39 | ||||
| IV. | A Comparison between the Respiratory Lesions of Influenza and those Initiated by the Inhalation of Poisonous Gases with Special Reference to:— | 40 | |||
| (A) The Inflammatory Response versus the Systemic Capacity to Compensate | 40 | ||||
| (B) The Primary Injury | 41 | ||||
| (C) The Tendency to Organization of Bronchiolar and Alveolar Exudates with Bronchiolitis and Bronchiolectasis as Sequelæ | 42 | ||||
| (D) The Importance of the Trachea and its Ramifications as a Protective Mechanism against Infection of the Pulmonary Parenchyma | 42 | ||||
| V. | Peculiarities of the Histology of Influenzal Pneumonia | 44 | |||
| (A) The Extent of the Initial Pulmonary Lesion | 44 | ||||
| (B) The Hemorrhagic Exudate—The Relation of Red to Grey Hepatization | 44 | ||||
| (C) The Aplastic Exudate | 45 | ||||
| (D) The Hyaline Necrosis of the Pulmonary Tissue | 46 | ||||
| (E) The Organization Process | 46 | ||||
| VI. | Infection as a Possible Etiological Factor for Malignant New Growths | 48 | |||
| VII. | The Bacteriology of Influenzal Pneumonia | 49 | |||
| (A) Organisms Associated with Influenzal Pneumonia | 49 | ||||
| (B) The Relation of the Type of Organism to Pleural Involvement | 50 | ||||
| (C) The Relation of Different Organisms to the Type of Pneumonia | 50 | ||||
| (D) Summary and Discussion | 54 | ||||
| VIII. | Conclusions | 55 | |||
| IX. | Bibliography | 56 | |||
| X. | Illustrations | 63 | |||
FIG. II. AUTOPSY NO. 98. DRAWING OF A SECTION THROUGH A TRACHEA SHOWING NECROTIZING HEMORRHAGIC INFLAMMATORY PROCESS OF THE MUCOSA.