Causes of the disappearance of poison from the body.—Chemical evidence is not always attainable in cases of poisoning. Various causes may remove the poison beyond reach. Hence although poison be not detected in the body,—the experimenter being supposed skilful and the poison of a kind which is easily discovered,—still it must not be concluded from that fact alone that poison has not been the cause of death. For that which was taken into the stomach may have been all discharged by vomiting and purging, or may have been all absorbed, or decomposed; and that which has been absorbed into the system may have been all discharged by the excretions.

1. It may have been discharged by vomiting and purging. Thus on the trial of George Thom for poisoning the Mitchells, held at Aberdeen at the Autumn Circuit of 1821, it was clearly proved, that the deceased had died of poisoning by arsenic; yet by a careful analysis none could be detected in the stomach or its contents; for the man lived seven days, and during all that time laboured under frequent vomiting.[85] In a remarkable case related by Dr. Roget, arsenic could not be found in the matter vomited twenty-four hours after it had been swallowed;[86] in another related by Professor Wagner of Berlin, that of an infant who died in twelve hours under incessant vomiting after receiving a small quantity of arsenic, none could be detected in the stomach;[87] in another which I have described in a paper on arsenic, although the person lived only five hours, the whole arsenic which could be detected in the tissues and contents of the stomach did not exceed a fifteenth part of a grain;[88] in an American Journal there is a striking case of a grocer, who died eight hours after swallowing an ounce of arsenic, and in whose body none could be found chemically,—at a period however antecedent to the late improvements in analysis;[89] and in a case communicated to me not long ago by Mr. Hewson of Lincoln, where arsenic was given in solution, and death ensued in five hours, none of the poison could be detected either in the contents or tissues of the stomach by a careful analysis conducted according to the most modern principles.

Nevertheless, it is singular how ineffectual vomiting proves in expelling some poisons from the stomach. Those which are not easily soluble, and have been taken in a state of minute division, may remain adhering to the villous coat, notwithstanding repeated and violent efforts to dislodge them by vomiting. Many instances to this effect have occurred in the instance of arsenic. Metzger has related a case, where, after six hours of incessant vomiting, three drachms were found in the stomach.[90] Mr. Sidey, a surgeon of this city, has mentioned to me an instance of poisoning with king’s yellow, in which he found the stomach lined with the poison, although the patient had vomited for thirty hours. In three cases which I have investigated arsenic was detected, although the people lived and vomited much for nearly two days;[91] and Professor Orfila has noticed a similar instance in which that poison was found in the contents of the stomach, although the person had vomited incessantly for two entire days.[92]

It is not easy to specify the period after which a poison that has excited vomiting need not be looked for in the stomach. It must vary with a variety of circumstances whose combined effect it is almost impossible to appreciate, such as the solubility and state of division of the poison, the frequency of vomiting, the substances taken as remedies, and the like. When the poison is in solution and the patient vomits much, an analysis may be expected to prove frequently abortive, even though the individual survives but a few hours, as in Mr. Hewson’s case already noticed. In other circumstances, however, as various facts quoted above will show, poisons may frequently be found after two days incessant vomiting; and on the whole it may be stated, that the recent improvements in analysis render the period much longer than it has generally been, and would naturally be imagined. Metzger has related the case of a woman poisoned with arsenic mixed with currants, in whose body, after eight days of frequent vomiting, he found ten or twelve currants, which gave out an odour of garlic when burnt;[93] but here the dose, if there was really arsenic, must have been repeated recently before death, for it is not possible to conceive how currants could remain in the stomach so long, whatever may be thought of the possibility of arsenic remaining. It is farther proper to add, that Professor Henke of Erlangen, one of the highest living authorities in Germany, once found grains of arsenic in the gullet, although he found none in any other part of the body, of a person who survived the taking of the poison four days.[94] Allowing to this fact all the weight derived from the high name of its author, I must nevertheless express great doubt whether the arsenic was not repeated more recently before death.

2. The poison may have disappeared, because it has been all absorbed. It has several times happened that in the bodies of those poisoned with laudanum, or even with solid opium, none of the drug could be detected after death. Sometimes indeed it is found, even though the individual survived the taking of the poison many hours. Thus a case related by Meyer of Berlin, in which the person lived ten hours after taking the saffron-tincture of opium; and nevertheless it was detected in the stomach by a mixed smell of saffron and opium.[95] But more commonly it all disappears, unless the dose has been very large. In a case of poisoning with laudanum, which I examined here along with Sir W. Newbigging in 1823, none could be detected, although strong moral circumstances left no doubt that laudanum had been swallowed seven or eight hours before death. An instance of the same kind has been minutely related by Pyl. It was that of an infant who was poisoned with a mixture of opium and hyoscyamus, and in whose stomach and intestines none could be detected by the smell.[96] Similar observations have been often made on animals; and several additional cases of the same purport, occurring in man, will be related under the head of opium.

It might be of use to quote some of the numerous errors committed by medical witnesses, in consequence of having overlooked the effect of absorption in removing poisons beyond the reach of chemical analysis. But not to be too prolix, I shall be content with mentioning a single very distinct case in point, which happened at a Coroner’s Inquest in London, in 1823. A young man one evening called his fellow-lodger to his bedside; assured him he had taken laudanum, and should be dead by the morrow; and desired him to carry his last farewell to his mother and his mistress. His companion thought he was shamming; but next morning the unfortunate youth was found in the agonies of death. The moral evidence was not very satisfactory; but that is of little consequence to my present object. The point in the case I would particularly refer to is the declaration of the medical inspector, that laudanum could not have been taken, because he did not find any by the smell or by chemical analysis in the contents of the stomach.[97]

3. Poisons may not be found, because the excess has been decomposed.

Vegetable and animal poisons may be altogether destroyed by the process of digestion. This observation will explain why sometimes no poison could be found in cases of poisoning with crude opium or other vegetable solids. A French physician, M. Desruelles, has related the case of a soldier, who died six hours and a half after swallowing two drachms of solid opium, and in whose stomach nothing was found but a yellowish fluid, quite destitute of the smell of the drug.[98]

Some mineral poisons, such as corrosive sublimate, lunar caustic, and hydrochlorate of tin, are also decomposed in the stomach. But they are not removed beyond the reach of chemical analysis. The decomposition is the result of a chemical, not of a vital process; and the basis of the poison may be found in the solid contents of the stomach under some other compound form. Other poisons again may be apt to elude detection by altering their form, by combining with other substances, without themselves undergoing decomposition. Thus it appears from a case related by Mertzdorff of Berlin, that, in poisoning with sulphuric acid, after the greater part of the poison is discharged by vomiting, the remainder may escape discovery by being neutralized: For, although he could not find any free acid in the contents of the stomach, he discovered 4½ grains in union with ammonia by precipitation with muriate of baryta.[99]

It may be also right to mention another kind of decomposition which may render it impossible to detect a poison that has been really swallowed—namely, that arising from decay of the body. In several recent cases bodies have been disinterred and examined for poison months or even years after death. In these and similar cases it would be unreasonable to expect always to find the poison, even though it existed in the stomach immediately after death. Some poisons, such as oxalic acid, might be dissolved and then exude; others, such as the vegetable narcotics, will undergo putrefaction; and others, such as prussic acid, are partly volatilized, partly decomposed, so as to be undistinguishable in the course of a few days only. The mineral poisons, those at least which are solid, are not liable to be so dissipated or destroyed. Some authors, indeed, have said that arsenic may disappear in consequence of its uniting with hydrogen disengaged during the progress of putrefaction, and so escaping in the form of arseniuretted-hydrogen gas; and they have endeavoured to account in this way for the non-discovery of it in the bodies of the people who had been killed by arsenic, and disinterred for examination many months afterwards.[100] But the supposition is by no means probable: at least arsenic has been detected in the body fourteen months, nay, even seven years, after interment. For farther details, on this curious topic, the reader may turn to the article Arsenic.

On the whole, the result of the most recent researches is that the effect of the spontaneous decay of dead animal matter in involving poisons in the general decomposition appears to be much less considerable than might be anticipated. For this most important medico-legal fact, the toxicologist is indebted to the experimental inquiries of MM. Orfila and Lesueur.[101] The poisons tried by them were—sulphuric and nitric acids, arsenic, corrosive sublimate, tartar-emetic, sugar of lead, protomuriate of tin, blue vitriol, verdigris, lunar caustic, muriate of gold, acetate of morphia, muriate of brucia, acetate of strychnia, hydrocyanic acid, opium, and cantharides. They found that after a time the acids become neutralized by the ammonia disengaged during the decay of animal matter;—that by the action of the animal matter the salts of mercury, antimony, copper, tin, gold, silver, and likewise the salts of the vegetable alkaloids, undergo chemical decomposition, in consequence of which the bases become less soluble in water, or altogether insoluble;—that acids may be detected after several years’ interment, not always, however, in the free state;—that the bases of the decomposed metallic salts may also be found after interment for several years;—that arsenic, opium, and cantharides undergo little change after a long interval of time, and are scarcely more difficult to discover in decayed, than in recent animal mixtures;—but that hydrocyanic acid disappears very soon, so as to be undistinguishable in the course of a few days.

4. Lastly, the poison which has been absorbed into the system, and may consequently be detected in certain circumstances in the textures of the body at a distance from the alimentary canal, may also be removed beyond the reach of analysis, by being gradually discharged along with the excretions. It has been fully proved in recent times, that in poisoning with arsenic the poison may be found in ordinary cases, for some days after being swallowed, in the liver especially, but also in the other textures, in the blood, and in the urine; but that if a flow of urine be established and kept up, in nine or ten days, and sometimes much sooner, it can no longer be discovered anywhere by the nicest analysis.[102]

Is the discovery of poison in the body or the evacuations essential to establish a charge of poisoning? It was mentioned at the commencement of the present section, that the chemical evidence is generally, and correctly, considered the most decisive of all the branches of proof in cases of poisoning. But some toxicologists have even gone so far as to maintain that without chemical evidence, or rather, in more general terms, without the discovery of poison either in the body itself or in the evacuations,—no charge of poisoning ought to be held as proved. This, however, is a doctrine to which I cannot assent. In the preceding observations on the evidence of general poisoning it has been several times alluded to as unsound; and repeated opportunities of establishing exceptions will occur in the course of this work, under the head of individual poisons. At present it may be well to illustrate its unsoundness in reference to those charges of poisoning, where no particular poison is pointed at by the medical evidence, but where a whole class of poisons must be kept more or less in view. Even here I apprehend there may be sufficient evidence in the symptoms and morbid appearances, without any chemical facts,—to render poisoning so highly probable, that in conjunction with strong moral evidence, no sensible man can entertain any doubt on the subject. Several illustrations might be here given; and some will be found scattered throughout the work. In the present place a few instances will be mentioned which cannot be conveniently arranged any where else, and which are well worthy of notice, as being striking examples of the decision of questions of poisoning without chemical evidence.

A man of doubtful character and morals, well acquainted with chemistry and medical jurisprudence, and of disordered finances, was known to harbour a design on a friend’s wife, who possessed a considerable fortune. At last he one morning invited the husband to breakfast with him at a tavern; and they breakfasted, in a private apartment, on beef-steaks, fried potatoes, eels, claret, and rum. They had scarcely commenced the meal when his guest complained of feeling unwell; and soon afterwards he vomited violently. This symptom continued, along with excruciating pain in the belly, for a long time before the prisoner sent for medical aid; indeed he did not procure a physician till the sufferer had been also attacked with very frequent and involuntary purging. The physician, who, before seeing his patient, had received the prisoner’s explanation of the apparent cause of the illness, was led at first to impute the whole to cholera caught by exposure to cold; but on returning at seven in the evening, and finding the gentleman had been dead for an hour, he at once exclaimed that he had been poisoned. On the body being inspected much external lividity was found, contraction of the fingers, and great inflammation of the stomach and intestines, presenting an appearance like that of gangrene.[103] On analyzing some fluid left in the stomach, no arsenic or other poison could be detected. The attention of the inspectors was turned specially to arsenic, because the prisoner was proved to have bought that poison, and to have made a solution of some white powder in his kitchen not long before the deceased died. The prisoner in his defence stated, that the deceased had been for some time much weakened by the use of mercury, and while in this state was seized with cholera; and he likewise attempted to make it probable that the man, in despair at his not recovering from a venereal disease, might have committed suicide. The council of physicians who were required to give their opinion on the case state on the contrary, that the diseased was a healthy man, without any apparent disposition to disease; that there was no pretext whatever for supposing suicide; that the inflammatory state of the stomach and bowels supplied strong probability of poisoning with arsenic, but not certain evidence; that acute gastritis from natural causes is always attended with constipation; that the deceased presented symptoms of stupor and other signs of derangement of the nervous system remarked in rapid cases of poisoning with arsenic; that cholera is very rare at the end of November, the season when this incident occurred; and that the poison might well be discharged by vomiting. Although all the prisoner’s statements in defence were contradicted by satisfactory proof, and the medical evidence of poisoning was supported by a chain of the strongest general circumstances, the crime was considered by the court as not fully proved, because the prisoner could not be induced to confess, and because poison was not actually detected in the body. But on account of the very strong probability of his guilt, he was, in conformity with the strange practice of German courts in the like cases, condemned to fifteen years’ imprisonment.[104] In this instance—considering the kind of symptoms, their commencement during a meal, the rapidity of death, the signs of violent inflammation in the stomach after so short an illness, and the facility with which the absence of poison in the contents of the stomach may be accounted for, more especially if it be supposed that the poison was administered in solution,—I consider the medical evidence of death by poisoning so very strong, that, the general evidence being also extremely strong, the prisoner’s guilt was fully demonstrated.

A case of the same kind, but of still greater interest, is that of Mary Anne M’Conkey, who was tried at the Monaghan Assizes in 1841 for the murder of her husband. I am indebted for the particulars to Dr. Geoghegan, one of the principal Crown witnesses. The prisoner who had been too intimate with another man, and had been heard to express her intention of getting rid of her husband, was observed one day before dinner to separate some greens for him from the plateful intended for the rest of the family. None of the latter suffered at all. But her husband was taken violently ill immediately after dinner, and died; and a neighbour accidentally present, who partook, though sparingly, of the same dish with him, was also similarly and violently affected but recovered. The deceased before finishing the greens said they had a disagreeable sharp taste, and was seized soon after with burning at the heart, tenderness at the pit of the stomach, vomiting, coldness, a sense of biting in the tongue and tingling through the whole flesh, excessive restlessness, occasional incoherence, locked-jaw, clenching of the hands, and frothing at the mouth; and he expired three hours after the meal. His neighbour, two minutes after finishing his greens, experienced a sense of pricking in the mouth and burning in the throat, gullet, and stomach; then salivation, a feeling of swelling in the face without actual fulness, general numbness and creeping in the skin; next excessive restlessness, coldness of the integuments, dimness of sight, and stupor; about an hour after the meal he became speechless, repeatedly fainted, frothed at the mouth, and clenched his hands; vomiting ensued, with considerable relief, and subsequently he had frequent attacks of it, with purging, tenderness of the epigastrium, cramps, and tingling in the flesh; and from these symptoms he recovered so slowly as to be unable to work for five weeks. The only morbid appearance of any note in the body of the deceased was a number of irregular brownish-black patches on the inside of the stomach. No poison could be detected in the contents or tissues of the stomach; none could be discovered in the house except a corrosive-sublimate solution which the prisoner used for a gargle; and none could be traced into her possession. A variety of circumstances of a general nature, which are passed over here for brevity, as not strictly appertaining to the present view of the case, threw very great suspicion over the prisoner. The medical witnesses deposed, that poisoning could alone explain the medical circumstances; and Dr. Geoghegan was of opinion that death was owing to some vegetable poison, although he could not specify the particular substance. He suspected, however, that it was monkshood. In these views, when consulted by him before the trial, I entirely concurred. Considering the taste observed by the deceased at the time he ate the greens, the rapidity with which he was taken ill afterwards, and the very peculiar symptoms, unlike those of any natural disease with which physicians are acquainted, and agreeing with those which are produced by monkshood,—considering also that another individual, who partook of the same dish with him, was similarly and simultaneously attacked, and with a severity proportioned to the quantity he took, while other persons who ate the same food from a different dish, did not suffer at all,—it appears to me that poisoning was clearly established; and I also think that the general evidence brought home the charge of administering the poison to the prisoner. She was condemned and executed, and confessed before execution, that she did poison her husband, and that the substance she used was the powdered root of monkshood, which is well known as a poison to the peasantry of Monaghan under the name of Blue Rocket.

It is scarcely necessary to add, that great caution must be observed in applying the general principle here inculcated. But the opposite doctrine, that no charge of poisoning can be established without the discovery of poison in the body or in the evacuations, appears to me a great error, though upheld by no mean authority. Under that doctrine few criminals would be brought to justice, were they to resort to a variety of vegetable poisons, which in certain seasons are within the reach of every one.

Section IV.Evidence from Experiments on Animals.

Evidence from experiments on animals with articles supposed to contain poison is more equivocal than was once imagined. But it may be doubted whether some medical jurists have not overstepped the proper limits, when they hold it to constitute little or no proof at all.

Evidence from express experiments should rarely form part of a regular medical inquiry into a charge of poisoning. For in the first place, to make sure of performing an experiment well requires more experimental skill than the generality of practitioners can be expected to possess; then, as will seen in the sequel, evidence procured from this source can very rarely be more than presumptive; and lastly, if the quantity of poison in the suspected substance is great enough to affect one of the perfect animals, it may generally be recognized to a certainty by its physical or chemical properties.

For these reasons it is not likely, that, in an inquiry undertaken by a skilful toxicologist, he will put himself in the way of delivering an opinion on the force of such evidence. But it is nevertheless necessary for me to consider it in detail, because he may have to give his opinion regarding experiments made inconsiderately by others, or accidents caused by domestic animals eating the remains of substances suspected to be poisoned.

The matter subjected to trial may be either suspected food, drink, or medicine; or it may be the stuff vomited during life, or found in the stomach after death; or it may be the flesh of poisoned animals.

1. The evidence derived from the effects of suspected food, drink, or medicine is better than that drawn from the effects of the vomited matter or contents of the stomach. But an important objection has been made to both, namely, that what is poison to man is not always poison to the lower animals, and that, on the other hand, some of the lower animals are poisoned by substances not hurtful to man.

A good deal of obscurity still hangs over the relative effects of poisons on man and the lower animals. There are two species, however, whose mode of life in respect to food closely resembles our own, and which, according to innumerable experiments by Orfila, are affected by almost all poisons exactly in the same way as ourselves, namely, the cat and dog, but particularly the latter.

In general poisons act less violently on these animals; thus two drachms of opium are required to kill a middle-sized dog,[105] while twenty grains have killed a man, and undoubtedly less would be sufficient. It appears that one poison, alcohol, acts more powerfully on them than on man. There are also some poisons, such as opium, which, although deleterious to them as well as to man, nevertheless produce in general different symptoms. Yet the differences alluded to are probably not greater than exist between man and man in regard to the same substances; and therefore it may be assumed, that, on the whole, the effects of poisons on man differ little from those produced on the dog and cat.

The present objection is generally and perhaps justly considered a stronger one, when it is applied to other species of animals. But it must be confessed after all, that our knowledge of the diversities in the action of poisons on different animals is exceedingly vague, and founded on inaccurate research; and there is much reason to suspect, that, if the subject is studied more deeply, the greater number of the alleged diversities will prove rather apparent than real. Both reasoning and experiment, indeed, render it probable, that some orders, even of the perfect animals, such as the Ruminantia, are much less sensible than man to many poisons, and especially to poisons of the vegetable kingdom. But so far as maybe inferred from the only accurate inquires on the subject, their effects differ in degree more than in kind. Some exceptions will without doubt be found to this statement. For example, oxalic acid, besides inflaming the stomach, causes violent convulsions in animals, but in man it for the most part excites merely excessive prostration; and opium most generally excites in man pure sopor, in animals convulsions also. Other exceptions, too, exist by reason of functional peculiarities in certain animals. Thus irritant poisons do not cause vomiting in rabbits or horses, because these animals cannot vomit; neither do they appear to cause much pain to rabbits, because rabbits have not the power of expressing pain with energy. But exceptions like these, and particularly such as are unconnected with functional peculiarities, will probably prove fewer in number, and less striking than is currently imagined. For it is, on the other hand, well ascertained, that many, indeed most of the active poisons whose effects have been examined by a connected train of experiments, produce nearly the same effects on all animals whatever from the highest to the lowest in the scale of perfection. It has been fully proved, that arsenic, copper, mercury, the mineral acids, opium, strychnia, conia, white hellebore, hydrocyanic acid, cyanogen gas, sulphuretted hydrogen, and many others, produce nearly the same effects on man, quadrupeds, birds, amphibious animals, and even on fishes and insects.[106]

Accordingly there are cases, in which the evidence from experiments on animals with suspected articles of food is unequivocal. For example;—a sexton and his wife, who had got a bad name in their village in consequence of informing against the bailiff for smuggling, and who were on that account shunned by all the neighbours, accused the bailiff and his wife of having tried to poison them by mixing poison with their bread. Immediately after eating they were attacked, they said, with sickness, griping, swelling, and dizziness; and they added, that a cat was seized with convulsions after eating a part of it, had sprung away, and never returned. A large portion of the loaf was therefore sent to the Medical Inspector of the district; who reported, that it seemed exactly similar to another unsuspected loaf;—that, although he was not able to detect any poison, it might after all contain one,—vegetable poison particularly;—but that he could hardly believe it did, for he fed a dog, a cat, and a fowl several days with it, and they not only did not suffer any harm, but even appeared very fond of it.[107] In this case it was clear that poisoning was out of the question. On the other hand, the effects of some poisons on man may be developed so characteristically in animals as to supply pointed evidence. Thus, in the case of Mary Bateman, an infamous fortune-teller and charm-worker, who after cheating a poor family for a series of years, at last tried to avoid detection by poisoning them, it was justly accounted good evidence, that a portion of the pudding and the honey, supposed to have been poisoned, caused violent vomiting in a cat, killed three fowls, and proved fatal to a dog in four days, under symptoms of irritation of the stomach such as were observed in the people who died.[108]

It has been farther objected to experiments on animals with suspected articles of food, drink, or medicine, that it is difficult to administer poison to them in a state of concentration, and to prevent it from being discharged by vomiting. This objection, however, may be obviated by performing the experiment in the way recommended by Professor Orfila. A small opening is made into the gullet, previously detached from its surrounding connexions, the liquid part is introduced by a funnel thrust into the opening, and the solid portion previously made into little pellets is then squeezed down. Lastly, the gullet is tied under the aperture. The immediate effect of the operation is merely an appearance of languor; and no very serious symptom is observable till four or five days at soonest after the tying of the gullet. Hence if signs of poisoning commence within twenty-four hours, they are independent of the injury done by the operation.[109] This process requires some adroitness to execute it well. It cannot be tried successfully but by a practised operator, who, for reasons already given, would hardly ever try experiments of the kind with suspected articles. Mention is here made of it, therefore, chiefly because it is the best mode of experimenting in those cases in which it is necessary, as will presently be seen, to determine disputed points in the physiology of poisons.

I may here shortly notice a method which has been lately proposed for detecting poisons that enter the blood, and which is founded on their effects on animals. M. Vernière suggests that advantage may be taken of the extreme sensibility of the medicinal leech to procure at least presumptive evidence, when no evidence can be procured in any other manner. He has related some experiments to prove that the leech, when placed in the blood of dogs killed by nux-vomica, is affected even when the quantity of the poison is exceedingly small.[110] It is extremely doubtful whether any importance can be attached to this criterion, as every one knows that the leech is apt to suffer from a variety of obscure causes, and among the rest from some diseased states of the body.

2. In the case of the vomited matter or contents of the stomach there are other and weightier objections to experiments on animals.—In the first place, the poison which has caused death may have been either in part or wholly vomited before-hand, or absorbed, or transmitted into the intestines, or decomposed by the process of digestion. Secondly, though abounding in the matter vomited or which remains in the stomach, it may be so much diluted, as not to have any effect on an animal. And, thirdly, the animal fluids secreted during disease are believed to act occasionally as poisons.

The first two objections are so plainly conclusive as scarcely to require any illustration. It may be well, however, to mention as a pointed practical lesson, that Professor Orfila once detected a considerable quantity of arsenic in the contents of the stomach, where a prior investigation had shown that the same article produced no effect on two animals, and where the reporters from this and other circumstances declared, that in their opinion death was not owing to poison.[111]

The last objection is a very important one; but there is reason for suspecting that it has been a good deal exaggerated by medical jurists.—Animal fluids are certainly poisonous when putrid. The repeated and fatal experience of anatomists, together with the precise experiments of M. Gaspard and M. Magendie,[112] leave no doubt that putrid animal fluids, when introduced into an external wound, cause spreading inflammation of the cellular tissue; and although Magendie says he has found such fluids harmless when introduced into the stomach of dogs,[113] it is probable, from their effects on man, that they will act as irritants on animals not habituated to their use. I believe, too, that independently of putrefaction, vomited matter or the contents of the stomach may be apt to make dogs vomit on account of their nauseous taste; and perhaps we may infer, that they will also cause some of the other symptoms of poisoning with the irritants, particularly if not vomited soon after being administered.—As to the influence of disease in rendering the contents of the stomach deleterious, it is to be observed that the effects just mentioned are probably owing to the influence of disease on the secretions, but that beyond this we know very little of the subject. In authors I have hitherto found only one fact to prove that disease can render the contents of the stomach decidedly poisonous; and on the negative side of the question there exists no facts at all. Morgagni describes the case of a child who died of tertian ague, amidst convulsions, and in whose stomach a greenish bile was found, which proved so deleterious, that a little of it given with bread to a cock caused convulsions and death in a few minutes, and a scalpel stained with it, when thrust into the flesh of two pigeons, killed them in the same manner.[114] It is not easy to say what to think of this experiment; which, if admitted to the full extent of the conclusions deducible from it, would lead to the admission, that disease may impart to the secretions the properties of the most active narcotics. Farther researches are certainly required before this admission can be made unreservedly.

On the whole, it appears that in the present state of our knowledge, experiments or accidental observations on the effects of the contents of the stomach, or of vomited matter, on animals are equivocal in their import. At the same time it may be observed, as with regard to articles of food, drink, or medicine, that the effects of some poisons on man may be developed so characteristically on animals by the contents of the stomach, as to supply very pointed evidence indeed. Of the force of this statement the following example is a striking illustration. In the case of a girl, who was proved to have died of accidental poisoning with laudanum, the inspector evaporated the contents of the stomach to dryness, made an alcoholic extract from the residue, and giving this to several dogs, chickens, and frogs, found that they were all made lethargic by it, some of them oftener than once, and that a few died comatose.[115] Facts such as these, agreeing so pointedly with the known effects of the poison suspected, appear to me to yield evidence almost unimpeachable.

3. The effects of the flesh of poisoned animals, eaten by other animals, constitute the least conclusive of all the varieties of the present branch of evidence. For the flesh of animals that have died of poisoning is not always deleterious; while on the other hand flesh is sometimes rendered so by natural causes, as will be seen in the Chapter on Diseased and Decayed Animal Matter.

This subject stands much in need of careful and methodic investigation. And it is of more practical importance than might be imagined at first sight. For the question has actually occurred in a legal inquiry in this country,—Whether poisoning in the human subject may be caused by the flesh of a poisoned animal?

In regard to some poisons it is well established, that animals killed by them may be eaten with impunity, such as game killed with the wourali poison, or fish by cocculis-indicus. This seems the general rule. But it is not clear that all poisons are similarly circumstanced.

The only systematic researches hitherto undertaken on this question are some recently made at Lucca by Professor Gianelli; of which however I have only seen an abstract. He found that the blood, urine, and lungs of animals poisoned with arsenic acted as a poison on small birds, such as sparrows, whether the parts were taken from the body while the animal was alive, or after death; but that alcohol, cherry-laurel water, corrosive sublimate, sulphate of copper, tartar-emetic, acetate of lead, nitrate of silver, trisnitrate of bismuth, chloride of tin, sulphate of zinc, laudanum, acetate of morphia, strychnia, and cantharides, had no such effect.[116] Orfila has since shown some reason for doubting the conclusiveness of Gianelli’s investigations; and on repeating them, obtained such results as render it doubtful whether any reliance can be put upon experiments made upon small birds.[117] Guérard however has ascertained, that dogs, fed on the flesh and entrails of sheep which had taken arsenic, were attacked with vomiting and purging, became reduced in flesh, and at length would not eat what was put before them; but none of them perished, or seem to have been seriously ill. Arsenic was detected in their urine.[118]

The importance of the inquiry, which the preceding experiments are intended to elucidate, will appear from the following singular case, for the particulars of which I am indebted to the kindness of Mr. Jamieson of Aberdeen, who was employed by the authorities to investigate it. An elderly woman, who kept fowls which occasionally trespassed on a neighbour’s fields, one morning observed four of them very sickly; and in the course of the day they became so ill that she killed them. She cleaned and prepared two of them for cooking, buried another, and gave away the fourth to a beggar, who was afterwards lost sight of. Next day soup made with the half of one of the fowls was given to a little girl, who suffered severely from sickness and vomiting, and also to a cat, which was similarly affected for the whole evening. On the day afterwards the woman herself and a female lodger, took broth made with what remained of the fowls, and also ate the gizzards; but the remainder was thrown with the offal upon the dunghill. In the course of five or six hours both women were attacked with severe illness. One had sickness, vomiting and great coldness; but after encouraging the vomiting with hot water and then taking some spirits, she got better in the night-time, and next morning was pretty well. The other, who was the owner of the fowls, was seized somewhat later than her friend with great thirst and shivering, and next day with pains in the stomach, severe sickness, and fruitless efforts to vomit. On the sixth day, when a medical man first saw her, she had great pain throughout the abdomen, much thirst, difficult breathing, a red, dry tongue, and a very frequent, small pulse. Next day the pain and difficult breathing became worse; and in the evening, after an attack of sneezing, she became gradually insensible and motionless, in which state she remained till the tenth day, when she expired. The stomach and intestines did not present any distinct morbid appearance; but the vessels of the brain were turgid, there were about two ounces of serosity in the lateral ventricles, both corpora striata were softened anteriorly, and a clot of blood as big as an almond was contained in the right anterior lobe of the brain.—A judicial investigation being ordered, it was ascertained that the fowl which the woman buried as well as the remains of the other fowls which were thrown upon the dunghill, had been carried off. But on searching the dunghill more carefully afterwards, the contents of one of the crops, which had been taken out and examined by the lodger, were discovered in the rubbish; and in the mass Mr. Jamieson detected a considerable quantity of arsenic.

This incident happened in 1836. More lately the same gentleman met with another extraordinary attempt of the same kind. A farmer, about to be married, gave directions for killing in the evening some fowls which were to be sent to the house of his bride where the ceremony was to take place. The killing of them however was accidentally delayed; and next morning, on the hen-house door being opened, the fowls ran furiously to the well, drank water incessantly, and died in an hour. On examining the bodies, Mr. Jamieson found arsenic in large quantity in their crops and gizzards.

On each of these occasions a particular individual came under suspicion; but the evidence against them was too slight to justify the authorities in bringing a formal charge; and consequently the proceedings did not go farther. In the former instance the evidence in favour of the flesh of poisoned animals being sometimes poisonous is strong; and the history of the woman’s case, although death seems to have been caused directly by apoplexy, renders it probable that even dangerous results might accrue.

The preceding remarks will enable the medical witness to know under what circumstances accidental observations or intentional experiments on animals furnish satisfactory proof.

Before quitting the subject, however, I have to add, that there is another purpose, besides procuring direct evidence, to which experiments with animals may be applied with great propriety;—namely, the settling disputed questions regarding the physiological and pathological properties of a particular poison. The science of toxicology is not yet by any means so perfect, but in particular cases topics may arise, which have not hitherto been investigated, and which it may be necessary to determine by experiment. Experiments on animals instituted for such purposes by a skilful toxicologist are not liable to any important objection. On the trial of Charles Angus at Liverpool in 1808, for procuring abortion and murder by poison, a trial of great interest, which will be referred to more particularly afterwards, it appeared from the evidence of the crown witnesses, that the poison suspected, corrosive sublimate, could not be discovered in the stomach by certain methods of analysis; and that, although corrosive sublimate is a powerful irritant, the villous coat of the stomach was not inflamed. But then it was proved by experiments made by one of their number, Dr. Bostock, that animals might be killed with corrosive sublimate without the stomach being inflamed, and without the poison being discoverable after death by the tests he used in the case.[119] An attempt was made on the side of the prisoner to throw out this line of evidence as incompetent, on the ground of the discrepant effects of poisons on man and on the lower animals. But it was admitted by the judge, on the plea that it was only to illustrate a general physiological fact, and not to infer proof of poisoning. The importance of experiments on animals to settle incidental physiological questions has lately been again acknowledged in a very pointed manner in an English court of law: for a set of experiments, to settle the question of the rapidity with which hydrocyanic acid acts, was instituted before the trial by the medical witnesses, at the request of the judge who was to try the case.[120]

Section V.Of the Moral Evidence.

It is not my object to treat under this head of the moral evidence generally, which is required to establish a charge of poisoning. But as it is well known that in criminal trials medical witnesses have for the most part nothing to do with the moral proof, while at the same time in cases of poisoning the medical and moral circumstances are always intimately interwoven and apt to be confounded together, it is necessary for me to specify those particulars of the moral evidence, which either require some medical skill to appreciate them, or fall naturally under the cognizance of the physician in his quality of practitioner. I shall enter into greater details under this section than may perhaps appear to the medical reader necessary, chiefly that I may redeem the pledge given in the introduction to the lawyer and general reader, and endeavour to show how powerful an instrument a medico-legal investigation may become in skilful hands, for throwing light on almost every branch of the evidence.

The moral or general proof in charges of poisoning is almost always circumstantial only. The circumstances of which it usually consists relate, 1. To suspicious conduct on the part of the prisoner before the event, such as dabbling with poisons when he has nothing to do with them in the way of his profession, or conversing about them, or otherwise showing a knowledge of their properties not usual in his sphere of life:—2. To the purchase or possession of poison recently before the date of the alleged crime, and the procuring it in a secret manner, or under false pretences, such as for poisoning rats when there are none on his premises, or for purposes to which it is never applied:—3. To the administration of poison either in food, drink, medicine, or otherwise:—4. To the intent of the prisoner, such as the impossibility of his having administered the poison ignorantly, or by accident, or for beneficial purposes, alleged or not alleged:—5. To the fact of other members of the family besides the deceased having been similarly and simultaneously affected:—6. To suspicious conduct on the part of the prisoner during the illness of the person poisoned,—such as directly or indirectly preventing medical advice being obtained, or the relations of the dying man being sent for, or showing an over-anxiety not to leave him alone with any other person, or attempting to remove or destroy articles of food or drink, or vomiting matter which may have contained the poison, or expressing a foreknowledge of the probability of speedy death:—7. To suspicious conduct after the person’s death, such as hastening the funeral, preventing or impeding the inspection of the body, giving a false account of the previous illness, showing an acquaintance with the real or supposed effects of poison on the dead body:—8. To the personal circumstances and state of mind of the deceased, his death-bed declaration, and other particulars, especially such as tend to prove the impossibility or improbability of suicide:—9. To the existence of a motive or inducement on the part of the prisoner, such as his having a personal quarrel with the deceased, or a hatred of him,—his succeeding to property by his death, or being relieved of a burthen by it,—his knowing that the deceased was with child by him.

Upon many of the particulars now enumerated, important evidence may be derived from the medical part of the investigation; and not unfrequently such evidence can be collected or appreciated only by means of a medico-legal inquiry.

1 and 2. On the first two articles, suspicious conduct or conversation on the part of the prisoner before the crime, and the possession or purchase of poison by him, little or nothing need be said. The medical witness may of course be asked whether the conduct or conversation proved betokens an unusual acquaintance with poisons and their effects. And his opinion may be referred to regarding the nature of suspected articles found in the prisoner’s possession. As to the purchase of arsenic under the false pretence of poisoning rats, it may be observed, that a great deal more stress is usually laid on such evidence than it seems to deserve; for there are few houses, in the country particularly, which are not more or less infected by them. On the other hand, too little weight is attached to the circumstance of the purchaser not having warned his household of poison being laid. Such conduct ought in my opinion to be accounted extremely suspicious; for so far as I have remarked, the fear with which unprofessional persons regard the common poisons is such, that I can hardly believe any master of a house would actually lay poison without warning the servants and other inmates of his having done so.

3. The next article, which relates to the proof of the administration of poison, will require some details.

Direct proof of the administration of poison by the actual giver is very rarely attainable, that part of the transaction being for the most part easily concealed. The proof of this point is justly accounted, however, a very important part of the evidence; nay, on some recent trials in this country the prosecution has failed apparently for want of such evidence, although the case was complete in every other particular. It is generally constituted by a chain of circumstances, and these are often strictly medical, as will now be shown by a few examples.

In the first place, pointed evidence as to the individual who gave the poison may be derived from the chemical investigation,—for example, from the comparative results of the analysis of the poisoned dish, and of the articles of which it consisted. I am indebted to my colleague, Dr. Alison, for the following excellent illustration from the case of William Muir, who was condemned at Glasgow in 1812 for poisoning his wife. In the course of the day on which she took ill she was visited by a farmer of the neighbourhood, who had studied physic a little in his youth. He learned from her that she had breakfasted on porridge a short time before she felt herself ill, and that she suspected the porridge to have been poisoned. He immediately procured the wooden bowl or cap in which the cottagers of Scotland keep the portion of meal used each time for making the porridge; and finding in it some meal, with shining particles interspersed, he wrapped a sample in paper, and took the proper measures for preserving its identity. He then secured also a sample from the family store in a barrel. The two particles were produced by him on the trial; and from experiments made in court the late Dr. Cleghorn was enabled to declare, that the meal from the bowl contained arsenic, and that the meal from the barrel did not. These facts, besides proving that the woman had next to a certainty taken arsenic in the porridge, likewise, in conjunction with other slight moral circumstances, established that the poison had been mixed with the meal in the house, and on the morning when the deceased took ill, before any stranger entered the house. The procedure of this farmer was precisely that which ought to be followed by the medical practitioner in a similar conjuncture.

An instance of an opposite description related by M. Barruel also deserves notice, as showing how evidence of this kind may afford, in otherwise suspicious circumstances, a strong presumption of accidental poisoning. Sixteen people near Bressières in France having been severely affected with vomiting and colic immediately after dinner, the bread, which was suspected, was examined by Barruel, and found to contain a little arsenic. The flour of which the bread was made had been taken from a large store of it, which, on being examined, was also found to be similarly impregnated. As it was extremely improbable that any one either could or would poison so large a mass of flour, to attain any malicious object, it was inferred that the arsenic had been mixed with it accidentally, and that the accident might have arisen from grain having been taken by mistake to the flour-mill to be ground, which had been intended originally for seed, and sprinkled with arsenic to destroy insects.[121]

It may be worth while observing, in the present place, that in the instance of poisoned wine very important evidence may be obtained by examining whether the wine with which the cork is impregnated contains any traces of the poison. This method of investigation occurred to me in a very singular case of poisoning with arsenic in champagne, which happened in a baronet’s family in Scotland. In this instance, however, such analysis was proved to be unnecessary; for the gentleman himself brought the bottle from his cellar, broke the wires and drew the cork, immediately before the wine was drunk.[122]

All evidence of the like nature, though it is at present often procured from other sources, should, for obvious reasons, be invariably collected, if possible, with the aid of a medical person. If again a medical man is called to a patient evidently affected with suspicious symptoms, and finds himself obliged to declare such to be his opinion, his thoughts, as soon as he has given directions for the treatment, should be turned towards that part of the evidence, for the securing of which he is naturally looked to as the person best qualified by previous education and his opportunities at the moment. With this view, therefore, having ascertained in what articles it is possible for poison to have been administered, he should at once endeavour to secure the remains of the particular portion partaken of by his patient, as well of the general dish, if it is an article of food, and of the ingredients of which the dish was ostensibly made, not forgetting the salt with which it was seasoned. A case occurred some years ago in the north of Scotland, in which arsenic was administered in porridge by mixing it with the salt.

It is of great consequence, before proceeding to analyze such articles, for example suspected dishes,—to be particular in investigating every thing connected with the cooking, serving, and eating of them. By doing so, not only will the chemical analysis be facilitated, but likewise facts in it will be accounted for, which might otherwise prove embarrassing, and even lead to the drawing of false conclusions from the result of the analysis. This statement is very well exemplified by the following incident which occurred to myself. In 1827 a family in Portobello were poisoned by the maid-servant; and it was believed, that, for the sake of a trick, she had, while carrying to the oven the beef subsequently used at dinner, maliciously mixed with it tartar-emetic or some other poison. One-half of the beef having been preserved, and two persons of the family having been very severely affected, Dr. Turner and I, to whom the case was remitted, made little doubt that we should discover the poison by chemical analysis: but we did not. Being subsequently employed by the sheriff to inquire into the particulars, I found that the poison had been mixed with the gravy, which had been consumed almost to the last drop,—that the gravy had been poured over the beef,—that the upper half of the beef had been eaten,—and that the remainder which we analysed had been transferred upon a different plate from that on which it was served for dinner. These particulars accounted sufficiently for the poison not having been discovered.

Another mode in which the chemical part of the inquiry may contribute to discover the individual who administered the poison is by a comparative examination of the persons of the deceased and the accused. The following very pointed illustration has been published by MM. Ollivier and Chevallier of Paris.—A woman who lived on bad terms with her husband was found dead on a roadside the morning after having been seen drunk in his company in the neighbourhood. The mouth, throat, and gullet were proved by a careful analysis to be corroded with nitric acid, the stains and traces of which were also found on various parts of her dress, and on the hair, neck, and arms, but not on her hands, and not lower down the alimentary canal than the upper fourth of the gullet. Ollivier, suspecting from these appearances, that she had not taken the acid voluntarily, requested to see the husband; whereupon there were found on his coat, trousers, and hands, a great number of stains, which, like those on the deceased, were proved by chemical analysis to have been produced by nitric acid. Here it was scarcely possible to avoid inferring, that the man got these stains while endeavouring to force his intoxicated wife to take the poison Marks of nail scratches were also observed round the mouth and on the throat; whence it was reasonably inferred, that, having failed in his original plan, he had suffocated her with his hands.[123]

While these illustrations are given of the conclusiveness of the chemical evidence in fixing the administration of poison on a particular individual, it is essential likewise to observe that the same kind of evidence may be at times equally conclusive of the innocence of a person unjustly suspected. This obvious and important application of a chemical inquiry is forcibly suggested by the following particulars of an incident related by M. Chevallier:—An individual was accused by a woman of having tried to poison her; and she represented that he had put the poison into her soup, while it stood from one day to another in an iron pot. On making a careful analysis of some of the soup which remained, Chevallier found it so strongly impregnated with copper, that, supposing the sulphate was the salt mixed with the soup, ten ounces must have contained twenty-two grains. It then occurred to him, that it was important to examine the iron pot, in which the poisoned soup was represented to have been kept; for the probability was that a large quantity of the copper, if any salt of that metal had really been contained in the soup, would have been thrown down by the superior affinity of the iron, and consequently that a coppery lining would be found on the inside. He was led, however, to anticipate that no copper would be found there, because there was no iron dissolved in the soup, as would have been the case if copper had been precipitated from it by the iron of the pot. And accordingly he not only found no copper lining the inside of the pot; but likewise, on following the process described by the accuser as the one pursued in cooking the soup and in subsequently poisoning it, he satisfied himself by express trial that there was nothing in the circumstances of the case which could have prevented the iron from exerting its usual action on the salts of copper. These conclusions, coupled with certain facts of general evidence, proved substantially that the suspected person had nothing to do with the crime charged against him; and he was therefore discharged.[124] A case somewhat similar will be related under the head of Imputed Poisoning.

In the second place, evidence as to the person who administered the poison may be procured by considering the commencement of the symptoms, in relation to the time at which particular articles have been given in a suspicious manner by a particular individual. The import of facts of this nature can be properly appreciated only by the medical witness; for he alone can be acknowledged as conversant with the symptoms which poisons produce, the intervals within which they begin to operate, and the circumstances in which their operation may be put off or accelerated.

Few cases will occur in which it is not possible to procure evidence of the kind, when diligently sought for. It is often too very decisive in its operation on judicial proceedings. In the case of Margaret Wishart tried at the Perth Spring Circuit in 1827 for poisoning her blind sister, a man who lodged with the prisoner and cohabited both with her and with the deceased, appeared at first from general circumstances to be implicated in the crime. He had left the house, however, on the morning of the day before that on the evening of which the deceased took ill; and he did not return till after her death. Now her illness commenced suddenly and violently; and arsenic was the poison which caused it.[125] It was quite clear, therefore, that the poison could not have been administered, at least in a dangerous dose, so early as the day before she was taken ill; and such I stated to be my opinion, on a reference from the Lord Advocate. The evidence being also otherwise insufficient, the man was set at liberty. In the case of Mrs. Smith tried here in February of the same year, this branch of the evidence was made the subject of question under more doubtful circumstances. The deceased certainly died of poisoning with arsenic, and the prisoner was strongly suspected of being the poisoner for many reasons, and among others because, on the evening before the morning on which the deceased took ill, the prisoner gave her in a suspicious manner a white-coloured draught. Here the possibility of the draught having been the cause of the symptoms must be admitted. But as they did not appear for eight hours after the draught was taken, I stated in my evidence that it was improbable the dose, if it contained arsenic at all, contained a quantity sufficient to cause the violent symptoms and death which followed.[126]

The correspondence in point of time between the appearance of symptoms of poisoning, and the administration of suspicious articles by an individual, constitutes still more decisive proof in a set of cases, in which it is of great value, as the chemical evidence is generally defective,—namely, where poisoning is attempted with repeated moderate doses. If the several renewals or exacerbations of illness correspond with the periods when suspicious articles have been given by the same individual, the circumstantial evidence of the administration may be even tantamount to direct proof. Thus, on the trial of Miss Blandy for the murder of her father, it was proved, that Mr. Blandy on several occasions, after the prisoner received certain suspicious powders from her lover, was taken ill with vomiting and purging; and that on two occasions recently before his death, when he got from his daughter a bowl of gruel which contained a gritty sediment, he was attacked after a very short interval with pricking and heat in the throat, mouth, stomach, and bowels,—with sickness, vomiting, gripes, and bloody diarrhœa.[127] Here the proof of administration by the prisoner was complete.

These examples will show how the evidence of a particular person’s criminality may be affected by the relation subsisting in point of time between the commencement of the symptoms and the suspicious administration of particular articles. But farther, the special period at which the symptoms begin may even at times supply strong evidence of his instrumentality, although there may be no direct proof from general evidence of his having been concerned in administering anything whatever in a suspicious manner. This statement is well exemplified by the case of Mrs. Humphreys, who was convicted at the Aberdeen Autumn Circuit in 1830 for poisoning her husband, by pouring sulphuric acid down his throat while he was asleep. It was clearly proved, as will be seen under the head of sulphuric acid, that the deceased died of this poison; and the administration was brought home to the prisoner in the following singular manner. The only inmates of the house were the deceased, the prisoner, and a maid-servant. The deceased got a little intoxicated one evening at a drinking party in his own house; and after his friends all left the house, and the street-door was barred inside, he went to bed in perfect health, and soon fell fast asleep. But he had slept scarcely twenty minutes, when he suddenly awoke with violent burning in his throat and stomach; and he expired in great agony towards the close of the second day. Now sulphuric acid, when it occasions the violent symptoms observed in this instance, invariably excites them in a few seconds, or in the very act of swallowing. It was, therefore, impossible that the man could have received the poison at the time he was drinking with his friends; and as he knew he had not taken any thing else afterwards, and it was fully proved that he had been asleep before his illness suddenly began,—it followed that the acid must have been administered after he fell asleep, the accomplishment of which was rendered easy by a practice he had of sleeping on his back with his mouth wide open. But, after he gave the alarm, the door was found barred as when he went to bed. Consequently no one could have administered the poison except his wife or servant; and it was satisfactorily proved, that no suspicion could attach to the latter. Such was one of the principal train of circumstances, which, as it were by a process of elimination, led to the inference that the wife was undoubtedly the person who administered the poison. Other circumstances of a similar tendency were also derived from the medical evidence; but these it is unnecessary to detail at present. I have related the particulars of the whole case fully elsewhere.[128] The prisoner strenuously denied her guilt after being sentenced, but confessed before her execution.

4. The next article in the moral evidence relates to the intent of the person who is proved to have administered poison. When the administration is proved, little evidence is in general required to establish the intent. It is sufficient that the giver knew the substance administered was of a deadly nature; and in regard to any of the common poisons this knowledge is sufficiently constituted by his simply knowing its name.

In some cases, however, the exact nature of the poison is not established with certainty; and then something else may be required to prove the prisoner’s knowledge, and through that knowledge his intent. In the case of Charles Munn, formerly alluded to [p. 50], arsenic was the poison presumed to have been taken by the deceased. But the purchase or possession of it by the prisoner was not for some time satisfactorily established; neither was there any chemical evidence, the deceased having lived forty days and upwards after taking the poison. It was proved, however, that whatever it was which had been administered, the prisoner knew very well that what he gave was deleterious; because he persuaded the deceased, who was pregnant by him, to take it by assigning to it properties which no drug either possesses, or is so much as thought by the vulgar to possess. On one occasion he persuaded her that it would show whether she was with child, and on another that it would prevent people from knowing she was with child. In such cases, then, good evidence may be derived from the arguments used by the giver to persuade his victim to take the poison; and sometimes, as in the instance now mentioned, it will lie with the medical witness to inform the court whether or not the reasons assigned are false.

Sometimes it has been pleaded by the prisoner that he gave the poison by mistake. In all such cases, if he descends to particulars, which he cannot help doing, there is every likelihood that the falsehood of the defence will be made evident by the particulars of the story not agreeing with other particulars of the moral or medical evidence. At present it is only necessary to allude to inconsistencies in his story with the medical facts. No general rules can be laid down on the method of investigating a case with a view to evidence of this kind: I must be satisfied with an illustration from an actual occurrence. On the trial of Mr. Hodgson, a surgeon, at the Durham Autumn Assizes in 1824, for attempting to poison his wife, it was clearly proved, that pills containing corrosive sublimate, and compounded by the prisoner, were given by him to her in place of pills of calomel and opium, which had been ordered by her physician. But it was pleaded by him, that, being at the time intoxicated, he had mistaken, for the shop-bottle which contained opium, the corrosive-sublimate bottle which stood next it. This was certainly an improbable error, considering the opium was in powder, and the sublimate in crystals. But it was not the only one which he alleged he had committed. Not long after his wife took ill, the physician sent the prisoner to the shop to prepare for her a laudanum draught, with water for the menstruum. When the prisoner returned with it, the physician, in consequence of observing it to be muddy, was led to taste it, before he gave it to the sick lady: and finding it had the taste of corrosive sublimate, he preserved it, analyzed it, and discovered that it did contain that poison. The prisoner stated in defence, that he had a second time committed a mistake, and instead of water had accidentally used for the menstruum a corrosive-sublimate injection, which he had previously prepared for a sailor. This was proved to have been impossible; for the injection contained only five grains to the ounce, while the draught, which did not exceed one ounce, contained fourteen grains.[129]

I believe it must be allowed, that, as the medical inquiries preparatory to trial are commonly conducted without the inspector being made acquainted with the moral circumstances in detail, it is rarely possible for him to foresee what points should be attended to, with the view of illustrating the intent. But the case now related will show that it is impossible for him to render his inquiries too minute or comprehensive; and more particularly, it shows the propriety of ascertaining, whenever it is possible, not only the nature but likewise the quantity of the poison.

5. The next article among the moral circumstances,—the simultaneous illness of other members of the family besides the person chiefly affected,—depends for its conclusiveness almost entirely upon the researches and opinion of the medical witnesses.