CHAPTER XII

THE CIRCULATION OF THE BLOOD AND THE CIRCULATION OF THE HEAVENS

The discoverer of the circulation would have been no fit pupil of Aristotle if he had limited his ken to the microcosm; nor were such limitations common in an age when astrology was not so far out of countenance as now. We have found Harvey discussing "the element of the stars" and reverently affirming the dependence of all life upon the sun as well as upon its Creator. We have found him also, in dealing with the powers of the blood, affirming that "lower and corruptible things are subject to other higher and incorruptible things," and in that connection paraphrasing a passage in which Aristotle deals with "the Cosmos which is about the earth." Of this—that is, of the sum of things between our globe and the moon's sphere—the ancient philosopher says:—

"Of necessity it is conjoined, in a way, with the courses on high, so that its entire power is governed thence; for that which originates motion in everything must be recognized as first cause."[445]

In "the courses on high" the divine living existences of heaven circulated forever, ruling the lower Cosmos as cycle succeeded cycle in endless series and the seasons endlessly recurred. In a few pregnant words Aristotle had dealt with the results of this Cosmic circulation, as follows:—

"There is said to be a circle in the affairs both of mankind and of whatever else is possessed of natural motion and is subject to generation and corruption."[446]

It was in Harvey's lifetime that this stupendous circulation of the heavens "and all that is in them" received its death stroke. Throughout Harvey's years of study at Padua, Galileo had lectured there with great acclaim; and after Harvey's return to London discovery after discovery had followed Galileo's work with the telescope, and had dealt blow after blow to the ancient astronomy. The trial of Galileo had followed; and he had died in 1642, nine years before the publication of Harvey's work On Generation. Yet belief in the ancient astronomy died far harder than belief in the ancient physiology of the movement of the blood. The ancient astronomy was based on the evidence of every man's own eyes, and flattered human vanity with the doctrine that the whole universe was centered upon the globe of which the ordained possessor was the creature made in the image of God. Milton had visited Galileo, famous long before, near Florence in 1638; but in the "Paradise Lost," published in 1667,[447] Milton expressly treated the question between the ancients and the followers of Copernicus as an open one, though Copernicus had died in 1543. Indeed, we find Harvey himself, seven years after Galileo's death, speaking of "the reason why our knowledge of the heavenly bodies is uncertain and conjectural";[448] and saying of opponents of the circulation of the blood: "Nor do they find it satisfactory to set up new systems, as in astronomy, unless these explain all the phenomena."[449]

It need not surprise us, therefore, to find Harvey writing as follows in 1628 in the very act of naming his own great discovery:—

"I beg leave to call this motion circular in the same sense in which Aristotle said that air[450] and rain imitate the circular motion of the bodies on high.[451] For the earth, when wet and warmed by the sun, gives off vapor; the vapors are borne upward and condensed and, when condensed into rain, descend again and wet the earth. Thus, too, generation here below and, in like manner, the arising of tempests and meteors result from the circular motion of the sun, his approach and recession."[452]

In 1651, nine years after the death of Galileo, in the last words about the moving blood which Harvey published, he drew a parallel between the circulation of the microcosm and the mighty circulation of the macrocosm. This parallel is drawn just before the end of his final work, his treatise On Generation, in a passage of his Exercise On the Innate Heat, in words which may serve to sum up what has gone before. These words shall be quoted without further comment and shall bring our present study of Harvey to an end:—

"The following few points should be considered well by every diligent mind, and so the fact becomes established more clearly, that those remarkable virtues which learned men attribute to the spirits and the innate heat are appropriate to the blood alone; to say nothing of what is so wonderfully striking in the egg before aught of the embryo has appeared, and in the perfect and developed embryo also. To be sure, the blood, considered absolutely and by itself outside the veins and regarded as consisting of elements[453] and as composed of different parts,—some thin and serous, some thick and solidified,—is termed 'cruor' and is possessed of very few virtues, and those obscure. But the blood, when present within the veins as a part of the body, a generative part, too, and endowed with soul, being the soul's immediate instrument and primary seat—the blood, seeming also to have a share of another diviner body and being suffused with divine heat, certainly acquires extraordinary powers, and is analogous to the element of the stars. As spirits the blood is the hearth, the Vesta,[454] the household deity, the innate heat, the sun of the microcosm, the fire of Plato;[455] not because it shines, burns, and destroys, like common fire, but because it preserves and nourishes and increases its very self by its perpetual wandering motion. Moreover, the blood deserves the name of spirits because, primarily and before all other parts, it abounds in radical moisture, that is, in the final and most immediate form of nourishment; and the same fare wherewith the blood itself is nourished is made ready by it and given out to all other parts while it is coursing perpetually through the entire body. Indeed, the blood nourishes, fosters, and keeps alive all the parts which it constructs and adjoins to itself, even as the heavenly bodies above, especially the sun and moon, impart life to what is below, while they continue in perpetual circulation. Since, therefore, the blood acts beyond the powers of the elements and is potent with those virtues aforesaid, and also is the instrument of the supreme workman, no one ever will give praise enough to its wonderful and divine faculties."[456]

Let us end these studies by picturing to ourselves the memorable figure of the small white-haired man ensconced in one of his favorite nooks on the leads of his brother's house, musing upon the mystery of the circulation, and linking it with that of

"The shining powers, conspicuous afar
Against the ether, which to mortals bring
Winter and summer."[457]

INDEX

Air, and fire, 14;
and respiration, 15, 23, 31, 40;
and spirits, Harvey on, 29;
soul in, 147.

Alcmæon, 111.

Ancients, Harvey and, 2, 3.

Anima, 23, 103, 147.
See also Soul.

Animal spirits, 22, 25, 127.

Animals, Aristotle on, 105.

Aorta, 62.

Aphrodite, 149.

Aretæus, 55.

Aristotle, 2;
on air and fire, 14;
on animals, 105;
and "artery," 49;
on causes of man, 144;
on cosmos, 121;
on chick's heart, 48;
on ether, 123, 125;
on faculties, 104;
on fire and soul, 143;
onmfunction of heart, 48, 113;
on heart as psychological center, 50;
on heart as seat of motion, 52;
ignorant of function of muscle, 53, 84;
on innate heat, 14, 44, 139;
as leader of Harvey, 48, 53, 67;
on life, 104; on movement of blood, 53;
on pulsation of heart, 82;
on respiration, 15, 30;
on semen, 120, 128;
on sexes, 145;
on soul, 51, 104, 114;
on spirits, 21;
on spontaneous generation, 143, 145;
on sun and fire, 150;
on sun and generation, 151.

Arterial vein, 57.

Artery, Aristotle's use of word, 49;
bronchial, 38;
flow in, 99;
Galen's demonstration of blood in, 3;
venous, 30, 57.

Aselli, Gasparo, 10.

Aubrey, John, 2, 12.

Auricles, action of, 75, 87;
fibrillar contractions of, 75.

Automatic generation, 143.

Avicenna, 2.


Blood, as arising in liver, 56, 60;
Aristotle on movement of, 53;
arterial and venous, 35;
color of, 35;
as constructor, 153;
as divine, 156;
as the first to live, 68, 69, 75, 109;
Galen on movement of, 56;
Harvey on arterial and venous, 35;
as innate heat, 116;
as the last to die, 73, 109;
life in, 76;
palpitation of, 75;
primacy of, 64, 81;
the seat of soul, 103, 105, 156;
as source of heat, 80, 109;
and spirits, 117, 120, 127.

Bloodletting, Harvey on, 110.

Blood pressure, Hales on, 96;
Harvey on, 97.

Bronchial arteries, 38.


Capillaries, circulation of blood in, 98.

Chemistry, Harvey on, 12.

Chick, development of, 47, 71.

Chyle, 9.

Cicero, 2, 141.

Circulation of blood, in capillaries, 98;
and circulation of heavens, 154;
according to Columbus, 58;
and feeding of tissues, 7;
first announcement of, 4, 42;
Harvey on use of, 1, 43;
opposition to, 5, 62;
and primacy of blood, 64;
and primacy of heart, 42;
pulmonary, 27, 38, 58, 101;
physicians and philosophers on, 55, 60;
and respiration, 11;
use of, 1, 5, 8, 43.

Circulation of heavens, 154.

Cleanthes, 141.

Columbus, Realdus, on pores of septum, 27;
and pulmonary circulation, 27, 38, 58;
on spirits, 27, 30.

Copernicus, 118, 155.

Cosmos, 121, 154.

Critias, 112.

Cruor, 76, 117, 156.


Democritus, 132.

Descartes, 85.

Diastole as caused by heat, 80.

Diogenes, 111.


Empedocles, 20, 112, 132.

Empyema, 29.

Erasistratus, and valves of heart, 55;
and Galen, 61;
on spirits, 21.

Ether, 123, 125, 129.


Fabricius ab Aquapendente, 1.

Faculty, intellectual, 105;
motor, 105;
nutritive, 104;
sensory, 105.

Female, function of, 145.

Fernel, Jean, 118;
on innate heat, 117.

Fever, Harvey's view of, 46.

Fire, and air, 14;
not the source of innate heat, 119, 139;
and soul, 143;
and sun, 150.


Galen, 2, 3;
circulation opposed by followers of, 62;
demonstration of blood in arteries by, 3;
and Erasistratus, 61;
on function of muscle, 84;
and Harvey, 61;
on innate heat, 17, 44;
on mitral valve, 58;
on movement of blood, 56;
on net-like plexus, 24;
on respiration, 16, 22, 27;
on spirits, 22, 27.

Galileo, 96, 155.

Generation, automatic, 143;
causes in human, 144;
eternity in, 126;
spontaneous, 143, 145, 152;
and sun, 145, 151.


Hales, Stephen, 96.

Hamlet, 103.

Harvey, William, and ancients, 2, 3;
on arterial and venous blood, 35;
on blood-letting, 110;
on blood pressure, 97;
on cause of heart-beat, 79, 81, 86, 90;
on chemistry, 12;
on development of chick, 47, 71;
on eternity in generation, 126;
on fever, 46;
first announcement of circulation by, 4, 42;
on flow in arteries, 99;
on flow in veins, 95, 100;
as follower of Aristotle, 48, 53, 67;
on functions of blood, 114;
on function of heart, 45;
on function of muscle, 84;
and Galen, 61;
and "heart," 56, 92;
on heart as seat of sensation, 107;
on innate heat, 19, 33, 39, 44, 116;
Lecture Notes of, 4, 18;
on mechanism of heart-beat, 86;
on moderns, 2;
on nerve impulse, 32;
as observer, 6, 70, 78;
at Padua, 1, 155;
publications of, 3, 4, 18, 66, 67;
on pulmonary circulation, 38, 101;
on respiration, 12, 18, 26, 28, 31, 39;
on soul, 103, 106;
as speculator, 6, 7;
on spirits, 28, 31, 33, 127, 133;
on spontaneous generation, 152;
on sun and generation, 151;
on use of circulation, 1, 5, 8, 43;
on venous return, 95.

Heart, action of excised, 92;
action of heat on, 76;
Aristotle on function of, 48, 113;
Aristotle on pulsation of, 82;
Aristotelian primacy of, 42;
of chick, 47, 71;
as common sense-organ, 51;
as the first to live, 47;
Harvey's use of word, 56, 92;
as origin of life, 45;
pores of septum of, 27, 57;
primacy of, 42;
as psychological center, 50;
the seat of motion, 52, 107;
the seat of sensation, 107;
the seat of soul, 51, 114;
the source of innate heat, 43, 49, 113;
valves of, 15, 16, 55, 58, 62.

Heart-beat, cause of, 79, 81, 90;
mechanism of, 81, 86, 89.

Heat, action of, on heart, 76;
in semen, 119, 124, 128, 140, 143.

Heat, innate, Aristotle on, 14, 44;
blood as, 116;
blood as source of, 80, 109;
as cause of diastole, 80;
as cause of pulse, 81, 93;
Fernelius on, 117;
Galen on, 17, 44;
Harvey on, 19, 33, 39, 44, 116;
heart as source of, 43, 49, 113;
not from fire, 119, 139;
and respiration, 14, 15, 16, 18, 33, 39;
Scaliger on, 117;
and spirits, 126, 129.

Heavens, 121, 149;
circulation of, and circulation of blood, 154.

Heraclitus, 111.

Hibernating animals, 77.

Hippocrates, on respiration, 15, 20;
on spirits, 20;
works of, 15.

Hofmann, Caspar, 5.


Intellectual faculty, 105.

Intellectual soul, 105.


Lacteals, discovery of, 10.

Laurentius, 29.

Life, Aristotle on, 104;
in blood, 76.

Ligature, 42.

Liver as source of veins and blood, 56, 60.


Male, function of, 145.

Milton, 70, 124, 155.

Mitral valve, 58.

Moderns, Harvey on, 2.

Motor faculty, 105.

Motor soul, 105.

Muscle, function of, 84;
function of, unknown to Aristotle, 53, 84.


Natural spirits, 25, 27.

Nerve impulse, 26, 32.

Nervous system and spirits, 31.

Net-like plexus, 22, 24.

Nutritive faculty, 104.

Nutritive soul, 50, 105, 145.


Oxyhæmoglobin, 26.


Paracelsus, 118.

Pascal, Blaise, 96.

Philosophers versus physicians, 55, 60, 65.

Physicians versus philosophers, 55, 60, 65.

Planets, 122.

Plato, 23, 51, 112.

Pneuma, 20, 23, 127, 147, 148.
See also Spirits.

Pores of septum, 27, 57.

Porosities of tissues, 98, 100.

Portal vein, 8.

Powers of the elements, 130.

Primitive moisture, 131.

Psyche, 23, 104, 147.

Psychical spirits, 23.

Pulmonary circulation, 27, 38, 58, 101.

Pulse, as caused by heat, 81;
as dependent on heart, 83.


Quintessence, 124.


Respiration, and air, 15, 23, 31, 40;
Aristotle on, 15, 30;
and circulation, 11;
Galen on, 16, 22, 27;
Harvey on, 12, 18, 26, 28, 31, 39;
Hippocrates on, 15, 20;
and innate heat, 14, 15, 16, 18, 33, 39.

Rete mirabile, 24.


Scaliger, Julius Cæsar, 118;
on innate heat, 117.

Semen, Aristotle's view, of, 120, 128;
heat in, 119, 124, 128, 140, 143;
spirits in, 119, 128, 140, 148.

Semilunar valves, 15, 16, 55, 62.

Sensory faculty, 105.

Sensory soul, 51, 105, 145.

Sexes, Aristotle on, 145.

Socrates, 112.

Soul, in air, 147;
Aristotle on, 51, 104, 114;
in the blood, 103, 105, 156;
as cause of vital activity, 143;
and fire, 143;
Harvey's view of, 103, 106;
in the heart, 51, 114;
intellectual, 105;
motor, 105;
nutritive, 50, 105, 145;
sensory, 51, 105, 145.

Spirits, 20, 23, 127, 147, 148;
and air, Harvey, on, 29;
animal, 22, 25, 127;
Aristotle's view of, 21;
and blood, 117, 120, 127, 133;
Columbus on, 27, 30;
Erasistratus's view of, 21;
Galen's view of, 22, 27;
Harvey's view of, 28, 31, 33, 127;
Hippocrates's view of, 20;
and innate heat, 126, 129;
natural, 25, 27;
and nervous system, 31;
psychical, 23;
in semen, 119, 128, 140, 148;
vital, 22, 24, 27.

Spiritus, 20, 147.

Spontaneous generation, 143, 145, 152.

Sun and fire, 150.

Sun and generation, 145, 151.


Taenia, 42.

Thales, 111.

Tissues, feeding of, and circulation, 7.

Torricelli, Evangelista, 96.

Tricuspid valve, 55.


Universe of Aristotle, 121.

Uranus, 149.


Valves of heart, 15, 16, 55, 58, 62.

Veins, arising in liver, 56, 60;
flow in, 9, 95, 100.

Vena cava, as distributer of blood, 55;
Galen's view of, 56.

Venous artery, 30, 57.

Vesalius, 118;
on pores of septum, 27.

Vital spirits, 22, 24, 27.


Wind-egg, 135, 145, 151.