CHAPTER VII.

TRIUMPH OF INOCULATION.

It having come to pass, according to the boast of Dr. Kirkpatrick, that inoculation was regarded as “the most salutary practice ever discovered for restraining a very loathsome and destroying disorder, which it had nearly expunged from the catalogue of mortal diseases,” it was the aim of physicians and patients to reduce the trouble and hazard of the operation to the lowest terms possible. In the words of Dr. Jenner, “There was bleeding till the blood was thin, purging till the body was wasted to a skeleton, and starving on vegetable diet to keep it so;” and practitioners who promised to mitigate these rigours, placed themselves in the line of popularity and prosperity.

Among distinguished easy inoculators was a family named Sutton—“the Suttons” being a familiar name a century ago. Dr. Robert Sutton practised surgery and pharmacy at Debenham, in Suffolk, and went into inoculation with such energy that between 1757 and 1767 he operated on 2514 patients. His son, Robert, set up as inoculator at Bury St. Edmunds, where he did a large business; but a second son, Daniel, was the genius of the household. He had been acting as assistant to Mr. Bumstead at Oxford, and returned to his father in 1763 enthusiastic over a new plan of inoculation whereby the time of preparation was to be shortened, whilst the patients were to live in the open air. Old Sutton showed no favour for the projected innovation, whereon Daniel opened an inoculating house on his own account at Ingatestone, in Essex, advertising himself as inoculator on a new, safe, and sure method. The speculation answered. In 1764 he took 2000 guineas, and in 1765 his receipts were £6300. His fame spread throughout the country, and so many resorted to him that lodgings were scarcely to be had in and around Ingatestone. His practice in Kent was also extensive, and he was obliged to employ assistants. To crown his enterprise, he kept a parson—the Rev. Robert Houlton, to puff his skill and success. According to Houlton, the business of Daniel Sutton during three years was as follows—

Inoculated in 1764,1629
1765,4347
1766,7816
———
13,792

to which number was added 6000 inoculated by Sutton’s assistants, making a total of 20,000, without, said Houlton, a single death.[59]

Sutton was denounced as a quack, and if to reserve as one’s own, and to traffic in what is proclaimed to be for the common advantage of mankind, constitutes a quack, Sutton was one. Nevertheless, he was successful, and his success begot so much jealousy that he was indicted at the Chelmsford quarter sessions, but acquitted with the thanks of the grand jury for the lesson he had taught the Faculty.

Much ingenuity was exercised in ferreting out Sutton’s secret. His secret, so far as it was anything, was an open one; and supposing it necessary to infect men’s blood with variolous pus, and then to operate for their recovery, there would be much to say for Sutton’s procedure. His patients were obliged to go through a strict preparatory regimen for a fortnight, during which every kind of animal food, with the exception of milk, and all fermented liquors and spices were forbidden. Fruit of all sorts was allowed, unless on days when purges were taken. In the course of a fortnight a powder was thrice administered at bed-time, and a dose of salts on the succeeding morning. When the days of preparation were accomplished, the patient was taken to the inoculating house, where in the public room was found an array of people in various stages of smallpox. From one of these sufferers, the operator selected a pustule to his mind, opened it with his lancet, and, turning to the patient to be poxed, raised the cuticle on the outer part of his arm with the moist lancet, and pressed it down with his finger. This was the entire operation: no plaster or bandage was applied: and from that moment the patient was pronounced proof against smallpox, even if he should lie in bed with one suffering from the disease. Of course there remained the variolous affection to be dealt with. The regimen of preparation was continued unchanged, and a pill was taken nightly until the fever came on. None were allowed to rest in bed, except for sleep, but had to walk abroad and enjoy fresh air, even in winter weather. If a patient was too sick to go alone, he was supported by attendants; and when the fever was at its height, he was encouraged to drink copiously of cold water.

Much more was attributed to Sutton’s pills and powders than to his regimen, and these were no more than preparations of antimony and mercury, with which practitioners of all orders were only too familiar. Sutton, however, contrived to maintain his mystery until he had no longer occasion for it, and lived to recognise a successor in Jenner. He removed to London in 1767 in hope of enlarging his income, but like many other provincial celebrities, discovered that he had better have remained where he shone without rivals and detractors.

The Sutton regimen, so far as it might be described as “cool,” came into general favour, whilst what was called the hot regimen of warm rooms, bed, and cordials was correspondingly discredited. Contrasting the two methods, Sir George Baker, writing in 1771, observed—

I found that in the counties of Norfolk, Suffolk, and Essex, many thousands of people of all ages and constitutions, and some of them with every apparent disadvantage, had been inoculated with general good success; whereas at Blandford, in Dorset, out of 384 who were inoculated, 13 actually died, and many others narrowly escaped with their lives from confluent smallpox.[60]

A famous inoculator was Dr. Thomas Dimsdale of Hertford, a Quaker of easy principles. He published in 1766 a treatise entitled The Present Method of Inoculating for the Smallpox—an exposition of the most approved practice of the time, which, by one of those curious felicities of circumstance, conferred on him a European reputation; and in 1781, Tracts on Inoculation—a record of his opinions and adventures at home and abroad.

Dimsdale desired to universalise inoculation, but with circumspection. He recommended that the inhabitants of a suitable district should be dealt with as a whole and at once. That the names of all should be taken, and on a certain day that everyone, who had not had smallpox, should be inoculated. That the district should then continue in quarantine for about three weeks, at the end of which the danger and the fear of smallpox would cease, until an unpolluted generation should afresh accumulate. The project was not mere dreaming. Dimsdale was a man of influence and energy, and effected several complete inoculations of villages and parishes in Hertfordshire according to his plan. In later years, he combined banking with medicine, and the firm of Dimsdale, Fowler, and Co. of Cornhill originated with him and perpetuates his name.

Dimsdale’s practice lay chiefly among the upper classes, to whom he made matters very comfortable. As he wrote—

I do not enjoin any restriction in respect to diet, nor direct any medicines to be taken before the time of operation by such as appear to be in a proper state of health.[61]

He was satisfied with administering a powder on the evening of the day on which a patient was inoculated, consisting of calomel, tartar emetic, and crabs’ claws.

Whilst labouring to popularise inoculation, Dimsdale was strongly opposed to the trade therein passing to unauthorised hands—simple, safe, and salutary though he asserted it to be. Thus he averred—

The mischiefs arising from the practice of inoculation by the illiterate and ignorant are beyond conception.[62]

How illiteracy should affect inoculation, he left to conjecture. He apparently forgot that the practice was derived from people who made no pretence to literature, and whose efficiency and success were, moreover, set forth as warrant and encouragement for English imitation.

In 1775 a Society was formed for General Inoculation, and an hospital was opened for the purpose at Battle Bridge, on the site of what is now the Great Northern Railway station, King’s Cross. Dr. Lettsom, a popular Quaker physician, issued an appeal on behalf of the enterprise, and having invoked Dr. Dimsdale’s approval, a lively controversy ensued between the brethren—personal rather than profitable. Dimsdale disapproved of indiscriminate inoculation: he was ready to inoculate the whole world, but systematically, and under strict safe-guards. He pointed out that whatever might be the advantage to the individual, unless the inoculated patient was rigorously secluded, he would diffuse the disease from which he sought to be delivered, and that the price of his life might be the destruction of many. Dimsdale’s warnings were, however, slightly regarded, and inoculation was pursued with criminal recklessness. As Pascal observes, of all the faculties given to man, the most awful in its consequences is the power of standing amid a number of facts, and seeing such as we please to see, and being blind to the rest.

Specially remarkable in connection with the smallpox of last century was the exaggerated terror expressed for it by professional inoculators, and the little real terror manifested by the multitude. It was by no means the most fatal of diseases, nor was it a large factor in the common mortality. Wherever we test the matter by unbiased contemporary evidence, we find the outcry factitious: the dreadful and desolating malady from which Jenner delivered his country is merely a fiction continued by the vaccinators from the inoculators. For proof let us turn to the evidence of Dr. Alexander Monro, Professor of Medicine and Anatomy in the University of Edinburgh. The Faculty of Medicine in Paris had appointed a commission to inquire into the advantages of inoculation, which in the course of duty applied to Monro, who in response produced and published in 1765 An Account of the Inoculation of Smallpox in Scotland. He reported that from the introduction of the practice by Maitland in 1726, there had been 5554 inoculations effected in Scotland with 72 fatalities; that is to say about 140 annually with deaths 1 in 78, according to the confession of the inoculators themselves. Monro further stated that the practice was disliked in Scotland as “a tempting of Providence,” an unwarrantable risk of life for an uncertain advantage. Our present interest, however, is in the statistics of deaths from smallpox in Edinburgh for a series of twenty years thus adduced by Monro.

BurialsFromBurialsFrom
from allSmallpox.from allSmallpox.
Diseases.Diseases.
17441345167  17541215104
17451463141  1755118789
17461712[63] 128  17561316126
1747120071  17571267113
17481286167  1758100152
17491132192  17591136232
1750103864  1760112366
17511241109  17619036
17521187147  17621305274
1753110570  17631160123
——————————
12,709125611,6131185

Here we have a piece of valid experience with every advantage to the smallpox terrorist: for Edinburgh last century was a city contrived as if for the generation and perpetuation of smallpox. The population of 55,000 was lodged thickly in flats, in houses of many storeys, closely built in lanes and courts—a population densely compacted as any in Europe, with arrangements for cleanliness indescribable, at this day perhaps incredible. Yet in conditions so propitious to smallpox, we see before us the total outcome during a series of twenty years; and reprehensible as the result may appear to contemporary sanitarians, who hold, and rightly hold, that all zymotic diseases are preventible, yet it affected Monro with no anxiety or dismay: nor does the rate of mortality of old Edinburgh contrast unfavourably with that of the modern city. The case of Edinburgh, however, serves to show that in all cases when we hear of the ravages of smallpox before Jenner appeared as deliverer, our policy is to insist firmly upon the production of special and adequate evidence: it is monstrous that the assertions of common quacks, whether inoculators or vaccinators, should pass into tradition and be accepted as unquestionable verity.

We have, moreover, to observe that the mortality from smallpox in Edinburgh was infantile mortality: for as Monro testified—

The inhabitants of Scotland generally have the smallpox in their infancy or childhood; very few adults being seen in this disease. Whether this is owing to any particular constitution of the air, or of the people, or to the disease not being so much dreaded as to cause any to fly from the place where it is, or to the great intercourse which must be among the inhabitants of the towns, of which several, nay, many families enter to their houses by one common stair, while in the villages the peasants are generally assistant to their neighbours of whose family any is sick, it is not now necessary to inquire.

Not only were the habits of the people contributory to the diffusion of eruptive disorders, but likewise their food, of which oatmeal was the staple, whilst vegetables were few, fruit rare, and tea unknown. Hence many maladies had free course; and as Dean Ramsay relates, a girl on her arrival at Mrs. Betty Muirheid’s boarding-school in the Trongate, Glasgow, when asked whether she had had smallpox, replied, “Yes, mem, I’ve had the sma’pox, the nirls [measles], the blabs [nettle-rash], the scaw [itch], the kink-host [whooping-cough], the fever, the branks [mumps], and the worm [toothache].”


A last word as to Lady Mary Wortley Montagu. After a residence of twenty years in Italy, she returned to England to die, 21st August, 1762. On the west side of the north door in Lichfield Cathedral, there is a female figure, in marble, leaning on an urn inscribed M. W. M. The inscription runs—

SACRED TO THE MEMORY OF
THE RIGHT HONOURABLE
LADY MARY WORTLEY MONTAGU,
WHO HAPPILY INTRODUCED, FROM TURKEY,
INTO THIS COUNTRY,
THE SALUTARY ART OF INOCULATING THE SMALLPOX.
CONVINCED OF ITS EFFICACY,
SHE FIRST TRIED IT WITH SUCCESS
ON HER OWN CHILDREN,
AND THEN RECOMMENDED THE PRACTICE OF IT TO
HER FELLOW-CITIZENS.

THUS, BY HER EXAMPLE AND ADVICE,
WE HAVE SOFTENED THE VIRULENCE, AND
ESCAPED THE DANGER, OF THIS MALIGNANT DISEASE.
TO PERPETUATE THE MEMORY OF SUCH BENEVOLENCE,
AND TO EXPRESS HER GRATITUDE
FOR THE BENEFIT SHE HERSELF RECEIVED FROM
THIS ALLEVIATING ART,
THIS MONUMENT IS ERECTED BY
HENRIETTA INGE,
RELICT OF THEODORE WILLIAM INGE, ESQ.,
AND DAUGHTER OF SIR JOHN WROTTESLEY, BART.,
IN THE YEAR OF OUR LORD,
MDCCLXXXIX.

Whilst we do not resort to epitaphs for truth, we may discover in them what was taken for truth, or what was wished to be taken for truth. We have in the foregoing epitaph the legend which has caught the popular fancy, and which is likely to survive corrections innumerable. It is the custom of mankind to identify a common movement with some prominent or picturesque figure in the movement, and to suppress the rest. The practice is convenient, but it taints all history with fable.


It may be said that the practice of inoculation met with no active resistance in England during the last thirty years of last century. How widely and deeply it extended it would be difficult to determine. The probability is, that the mass of the population was untouched, and that inoculation was limited to the upper and middle classes, and to the lower so far as they came under the immediate influence of those above them. We have, perhaps, an index to the condition of affairs in Dr. Wm. Buchan’s Domestic Medicine, first published in 1769, which ran through eighteen editions, amounting to 80,000 copies, in the author’s life-time. It is not uncommon to refer contemptuously to Buchan, but his work was the production of a man of vigorous good sense with faith in the good sense of his readers—a book creditable to the author and to the people who appreciated him.

Buchan was an inoculator, a zealous advocate of inoculation, and earnestly laboured to universalise the practice. In the Domestic Medicine, ed. 1797, he wrote—

No discovery can be of general utility while the practice of it is kept in the hands of a few. Had Inoculation been practised by the same kind of operators in our country as in the countries from which we derived it, it had long ago been universal. The fears, the jealousies, the prejudices, and the opposite interests of the Faculty are, and ever will be, the most effectual obstacles to the progress of any salutary discovery. Hence it is that Inoculation never became in any manner general in England till taken up by men not bred to physic.

Consistently with this opinion, Buchan strongly advocated domestic practice, saying—

They know very little of the matter, who impute the success of modern inoculators to any superior skill, either in preparing the patient or communicating the disease. Some of them, indeed, from a sordid desire of engrossing the whole practice to themselves, pretend to have extraordinary secrets or nostrums for preparing persons for inoculation, which never fail of success. But this is only a pretence calculated to blind the ignorant and inattentive. Common-sense and prudence alone are sufficient both in the choice of the subject and management of the operation. Whoever is possessed of these may perform this office for his children whenever he finds it convenient, provided they be in a good state of health.

This statement is not the result of theory, but of observation. Though few physicians have had more opportunities of trying inoculation in all its different forms, so little appears to me to depend on those generally reckoned important circumstances, of preparing the body, communicating the infection by this or the other method, etc., that, for several years past, I have persuaded parents and nurses to perform the entire operation themselves.

I have known many instances of mothers inoculating their children, and never so much as heard of one bad consequence. Common mechanics often, to my knowledge, perform the operation with as good success as physicians.

Having described the ordinary method of inoculation by incision with a lancet dipped in pus, he goes on to say—

If fresh matter be applied long enough to the skin, there is no occasion for any wound at all. Let a bit of thread, about half an inch long, wet with the matter, be immediately applied to the arm, midway between the shoulder and the elbow, and covered with a piece of common sticking-plaster, and kept on for eight or ten days. This will seldom fail to communicate the disease.

Instead of multiplying arguments to recommend this practice, I shall beg leave to mention the case of my own son, at the time an only child. After giving him two gentle purges, I ordered the nurse to take a bit of thread which had been previously wet with fresh matter from a pock, and to lay it upon his arm, covering it with a piece of sticking-plaster. This remained on six or seven days, until it was rubbed off by accident. At the usual time smallpox made their appearance, and were exceedingly favourable. Surely this, which is all that is generally necessary, may be done without any skill in medicine.

Thus was smallpox made easy!

Buchan appealed to the clergy for co-operation as inoculators—

The persons to whom we would chiefly recommend the performance of this operation are the clergy. Most of them know something of medicine. Almost all of them bleed, and can order a purge, which are all the qualifications necessary for the practice of inoculation.

And as propagandists—

No set of men have it so much in their power to render the practice of inoculation general as the clergy, the greatest opposition to it still arising from some scruples of conscience, which they alone can remove. I would recommend them not only to endeavour to remove the religious objections which weak minds have to this salutary practice, but to enjoin it as a duty, and to point out the danger of neglecting to make use of a means which Providence has put in our power for saving the lives of our offspring. Surely such parents as wilfully neglect the means of saving their children’s lives are as guilty as those who put them to death.

How familiar have vaccinators rendered this line of adjuration! If you do not comply with our prescription, and your children catch smallpox, then are you their murderers.

Here is another passage from Buchan, which with equal accuracy might apply to Vaccination—is indeed what is perpetually asserted to be the truth concerning Vaccination—

As the Smallpox is now become an epidemical disease in most parts of the known world, no other choice remains but to render the malady as mild as possible. This is the only manner of extirpation now left in our power; and though it may seem paradoxical, the artificial method of communicating the disease, could it be rendered universal, would amount to nearly the same thing as rooting it out. It is a matter of small consequence whether a disease be entirely extirpated, or rendered so mild as neither to destroy life nor hurt the constitution; but that this may be done by Inoculation, does not now admit of a doubt. The numbers who die under Inoculation hardly deserve to be named. In the natural way, one in four or five generally dies; but by Inoculation not one of a thousand. Nay, some can boast of having inoculated ten thousand without the loss of a single patient.

In this deliverance, Buchan did not lie, nor did he speak for himself alone, but expressed the medical opinion of his time, precisely as a physician of to-day testifies concerning Vaccination. Yet we all know that Buchan was completely at fault, and substituted what he wished to be true for what was true.

I cannot leave Buchan without a few words in his favour, for, according to his lights, he was a worthy fellow, and the words shall be his own. He wrote—

I am old enough to remember the time when the success of Inoculation was supposed to be entirely owing to the preparation of the body, as it was called; but I am convinced that such preparation always has done, and still does, more harm than good. The body cannot be better prepared to meet a disease, than by being in good health. Medicine may cure a disease, but it cannot mend good health. When a person enjoys the blessing of health, he ought never to meddle with medicine on any account whatever.

No: nor with half an inch of thread dipped in pox.

FOOTNOTES:

[59] Sermon preached at Ingatestone, 12th October, 1766, in defence of Inoculation, with App. on the present state of Inoculation. Lond., 1767.

[60] Medical Transactions, vol. ii. art. xix.

[61] Tracts on Inoculation, p. 126.

[62] Ibid. p. 107.

[63] Monro accounts for the excessive mortality of this year by the presence of regiments in Edinburgh after the suppression of the rebellion of 1745.